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The Small Animal MRI System for rodents represents a cutting-edge, compact, and versatile imaging solution meticulously crafted for research and pre-clinical studies involving small rodents such as mice and rats. This system excels in delivering high-resolution, intricate images of the internal anatomy of small animals, offering researchers invaluable insights into organ and tissue anatomy and function.
Distinguished by its modest bore size, the system is tailor-made for rodent imaging and minimally invasive procedures. Its formidable magnetic field, coupled with advanced gradient technology, ensures outstanding image quality and heightened sensitivity, enabling researchers to visualize minute structures and details with remarkable clarity.
This MRI system is outfitted with state-of-the-art software and hardware, boasting real-time imaging capabilities and automated image processing tools. This streamlined functionality empowers researchers to swiftly and accurately obtain and analyze data. Moreover, the system’s flexibility is underscored by its customization options, allowing users to tailor both hardware and software settings to their specific imaging requirements.
Our Small Animal MRI System employs a permanent magnet system that not only produces high-contrast images but also features an intuitive user interface, enhancing user experience and facilitating seamless operation.
ConductScience offers the Small Animal MRI System.
| Specifications | Model 40H | Model 60H |
|---|---|---|
| Magnet Permanent | 1.0 ± 0.05T | 0.5±0.05T |
| Magnet uniformity | 20 ppm (40mm×40mm×40 mm) | ≤20ppm (60mm×60mm×60mm) |
| Magnetic field stability | ≤300Hz/Hour | ≤300Hz/Hour |
| Magnet temperature control | Dual system of nonlinear precise temperature control, temperature tunable from 25℃ to 35℃, temperature accuracy ±0.1℃; | Dual system of nonlinear precise temperature control, temperature tunable from 25℃ to 35℃, temperature accuracy ±0.1℃; |
| RF field: pulse frequency | 1-30MHz | 1-30MHz |
| Frequency control accuracy | 0.1Hz | 0.1Hz |
| RF power amplifier | > 300W | > 300W |
| Maximum bandwidth | 2000KHz | 2000KHz |
| MRI gradient | > 7.5 Gauss/cm for x, y, z | > 5 Gauss/cm for x, y, z |
| Standard probe size (Optional) | 40 mm | 60 mm, 40 mm or 25 mm |
| Effective detection size | 40 mm Probe: Up to Ø 40 mm | (1) 60 mm Probe: up to Ø 62mm (45 – 150 g mice) (2) 40 mm Probe: up to Ø 42mm (20 – 45 g mice) (3) 25 mm Probe: up to Ø 32mm (1 – 20 g mice) |
| Image quality | Graphic SNR >= 20db Image distortion ≤ 5% – Image uniformity >=70% | Graphic SNR >= 20db; Image distortion ≤ 5% – Image uniformity >=70% |
| Maximum data record length | Maximum CPMG is 18,000 | Maximum CPMG is 18,000 |
| Minimum echo time | 200 US (Based on PCI bus industrial control computer platform, 8-core CPU, 8G DDR memory, 1T hard disk) | 200 US (Based on PCI bus industrial control computer platform, 8-core CPU, 8G DDR memory, 1T hard disk) |
| Operating conditions | Power supply: 220V, 50Hz Temperature: 22-28°C Humidity: 30-70% | Power supply: 220V, 50Hz Temperature: 22-28°C Humidity: 30-70% |
| Dimensions (L, W, H) | (L, W, H): 1800mm× 800 mm×1200 mm; | Magnet box: 760 mm× 530 mm× 514 mm Control cabinet: 560 mm× 660 mm× 970 mm |
| Total weight | 1.1 tons | 800 kg (Magnet 700 kg, control cabinet 100 kg) |
The Small Animal MRI system is a low-field NMR (Nuclear Magnetic Resonance) apparatus. It is utilized for in-vivo MRI observation of small animals such as rodents. It has a wide range of applications in neurology, histology, and metabolism. The system provides high-contrast images using a powerful permanent magnet system with an intuitive user interface. Two models are available for small animal analysis.
Two models of the apparatus are available, a 40H model and a 60H model. The 40H model measures 1800 mm in length, 800 mm in width, and 1200 mm in height. It has a total weight of 1.1 tons, of which the magnet weighs 1.0 tons, and the control cabinet weighs 0.1 tons. The 60H model measures 700 mm in length, 530 mm in width, and 514 mm in height. The control cabinet measures 560 mm in length, 660 mm in width, and 970 mm in height. It has a total weight of 800 kg, of which the magnet weighs 700 kg, and the control cabinet weighs 100 kg.
It is equipped with a permanent magnet (1.0 ± 0.05T for the 40H model and 0.5±0.05T for the 60H model). The standard probe size for the 40H model is 40 mm, while the 60H model includes probe sizes of 60 mm and 40 mm with an optional 25 mm probe. It has a sensitivity volume of (Ø 40 mm× 40 mm). The 40H model magnet uniformity is 20 ppm (40mm×40mm×40 mm), while the 60H model magnet uniformity is ≤20ppm (60mm×60mm×60mm). The effective detection size of the 40 mm probe for the 40H model is up to Ø 40 mm. The 60H model’s effective detection size for the 60 mm probe is up to Ø 62mm (45 – 150 g mice), the 40 mm probe is up to Ø 42mm (20 – 45 g mice), and the 25 mm probe is up to Ø 32mm (1 – 20 g mice). The 40H model MRI gradient is > 7.5 Gauss/cm doe x, y, z, and the 60H model MRI gradient is > 5 Gauss/cm for x, y, and z.
The magnet’s field stability is ≤300Hz/Hour. The magnet has a dual system of nonlinear precise temperature control. The temperature is tunable from 25℃ to 35℃ with a temperature accuracy of ±0.1℃. . The RF field pulse is within the range of 1-30MHz with a frequency control accuracy of 0.1 Hz. The RF power multiplier is > 300W. The maximum bandwidth is 2000KHz. The image quality is graphic SNR >= 20db; Image distortion ≤ 5%; Image uniformity >=70%. The maximum data record length is 18000 CPMG. The minimum echo time is 200 US.
The following components are included with the apparatus
The Small Animal MRI System has several applications in the following fields
Analysis of In Vivo Hepatic Steatosis
Cui, Hu, Han, Yang, and Li (2017) utilized the Small Animal MRI System to analyze the body composition of mice to study hepatic steatosis. Eight-week-old male C57BL/6 mice were fed a high-fat and high-sucrose diet for four to sixteen weeks. This was done to induce obesity in the mice, which is one of the key risk factors of nonalcoholic fatty liver disease (NAFLD) of which Hepatic steatosis is the earliest stage of NAFLD. The Small Animal MRI System measured the body fat mass, lean mass, and fluids of the mice. The whole body of the mice and their livers were scanned using a 0.55 T magnet with the device. The results indicated that the subjects’ body weight increased to 45±1.2 g after 16 weeks of feeding on the high-fat, high-sucrose diet. Overall results from the MRI analysis indicated that hepatic steatosis and obesity increased with the high-fat and high-sucrose diet.
The Small Animal MRI System has a permanent tesla magnet that provides high magnetic field uniformity and minimal eddy current effect. The system allows high-quality anatomy imaging with a high resolution of < 0.08 mm. The MRI software is user-friendly. It includes multiple sequences for full MRI capabilities. The system is non-destructive, with no risk or negligible running costs since it doesn’t require cryogenic gases. Two models of the system are available to suit your experimental needs. The system can be used for several applications in several life science fields, including oncogenic research, pharmacological research, and studying obesity and cardiovascular disease models.
| Brand | Niumag Suzhou |
|---|---|
| Model | |
| Product Application | Analytical Instruments, Educational, Laboratory Equipment, Life Sciences, Magnetic Resonance Imaging (MRI), Medical Diagnostic Equipment, Pre Medical Analysis |
| Volts | 110V, 220V |
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DISCLAIMER: ConductScience and affiliate products are NOT designed for human consumption, testing, or clinical utilization. They are designed for pre-clinical utilization only. Customers purchasing apparatus for the purposes of scientific research or veterinary care affirm adherence to applicable regulatory bodies for the country in which their research or care is conducted.
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