Research data · Animal model

Aluminum chloride

From 2021 to 2025, 157 animal research papers mentioned aluminum chloride and at least one behavioral test.

That is 4.0 times the 39 papers of 2011 to 2015. Between the same two periods, all the animal research papers that mention any of the 90 tests we count grew more slowly, to 1.2 times as many.

157 animal research papers from 2021 to 2025 mentioned aluminum chloride and a test
4.0 times as many papers as in 2011 to 2015
61% of these papers mention the Morris water maze
31% of the 513 animal research papers from 2021 to 2025 that mention aluminum chloride also mention a test

The tests mentioned with aluminum chloride

The Morris water maze appears in 61% of these papers and in 17% of all 32,277 papers that mention a test. That makes it 3.6 times as common in this research. Each bar is one test, with how many of the 157 papers from 2021 to 2025 mention it, and what share that is. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

95 papers 61%
32 papers 20%
28 papers 18%
20 papers 13%
18 papers 11%
10 papers 6%
7 papers 4%
6 papers 4%
4 papers 3%
4 papers 3%
4 papers 3%
2 papers 1%
All 27 tests these papers mention
Papers from 2021 to 2025 that mention aluminum chloride and each test
TestPapersShare of the 157 papers
Morris water maze9561%
Y-maze3220%
Novel object recognition3120%
Elevated plus maze2818%
Passive avoidance2013%
Open field1811%
T-maze106%
Radial arm maze74%
Rotarod64%
Active avoidance (shuttle box)64%
Light-dark box43%
Forced swim test43%
Novel tank test43%
Beam walking21%
Tail suspension test21%
Wire hang and inverted grid21%
Hole-board21%
Social interaction test11%
Fear conditioning11%
Negative geotaxis and climbing assays11%
Grip strength11%
Object location test11%
Pole test11%
Nest building11%
Step-down avoidance11%
Barnes maze11%
Prepulse inhibition and acoustic startle11%

Tests named in 30 or more of these papers link to a page on that test with aluminum chloride. To count the papers that mention two or more tests together, use the test battery tool.

Papers by year

Animal research papers that mention aluminum chloride and a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20012
20022
20033
20041
20053
20063
20071
20082
20094
20102
20115
20124
20136
20146
201518
201615
201716
201814
201913
202023
202132
202234
202326
202424
202541
2026 (part year)45

Papers that mention aluminum chloride and a test fell from 32 in 2021 to 24 in 2024, then rose to 41 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. We take a paper's species from PubMed's indexing when the indexing names one. Otherwise PubTator 3, NCBI's text-mining service, has to find a species in the title or abstract, or the paper is not counted. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Disease models in papers that mention aluminum chloride

Each bar is one disease model, with how many of the 157 papers from 2021 to 2025 are tagged with it, and what share that is. The model comes from the paper's MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. A paper without MeSH terms gets its model from PubTator 3, NCBI's text-mining service, if PubTator 3 finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

113 papers 72%
8 papers 5%
4 papers 3%
2 papers 1%
1 paper 1%
1 paper 1%
1 paper 1%

Which species the papers used

Each bar is a share of the 157 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Rat
106 papers 68%
Mouse
44 papers 28%
Zebrafish
9 papers 6%
Other animals
1 paper 1%

“Other animals” counts papers that use none of the species this chart names.

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention aluminum chloride and a behavioral test and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer's disease in rats.

    Saudi J Biol Sci, 2021. 83 citations.

  2. Effects of melatonin and resveratrol on recognition memory and passive avoidance performance in a mouse model of Alzheimer's disease.

    Behav Brain Res, 2021. 69 citations.

  3. Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-κB/p38MAPK/BDNF/PPAR-γ pathways.

    J Ethnopharmacol, 2021. 66 citations.

  4. AlCl3 induced learning and memory deficit in zebrafish.

    Neurotoxicology, 2022. 52 citations.

  5. Protective Effect of Ginkgolide B against Cognitive Impairment in Mice via Regulation of Gut Microbiota.

    J Agric Food Chem, 2021. 50 citations.

How we counted

A paper counts here when it is animal research and its title or abstract mentions aluminum chloride and at least one of the 90 behavioral tests. A count is a number of papers, not of experiments, labs or animals. A paper that mentions aluminum chloride only in its methods is missed, so the count runs low.

A paper is animal research when its MeSH terms name an animal species. If they name none, NCBI's text-mining service PubTator 3 has to find one in the title or abstract. Papers on animals other than mice, rats, zebrafish, flies and primates count only when they also mention a test. Many of them study people or use the same words for something else.

The search terms for aluminum chloride are in the download Animal models and brain techniques. The counts in the chart of tests are in Tests mentioned with each model or technique. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More animal models

Each animal model with 100 or more papers from 2021 to 2025 that mention a test has a page. These are the others, each with that count.

How to cite

APA

ConductScience. (2026, November 13). Behavioral tests with aluminum chloride [Data set]. https://conductscience.com/resources/data/animal-models/aluminum

BibTeX

@misc{conductscience_aluminum_2026,
  author = {{ConductScience}},
  title = {Behavioral tests with aluminum chloride},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/animal-models/aluminum},
  note = {Data set, released November 13, 2026},
}

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