Research data · Animal model

Carotid artery occlusion (BCCAO, 2VO)

From 2021 to 2025, 264 animal research papers mentioned carotid artery occlusion (BCCAO, 2VO) and at least one behavioral test.

That is 1.5 times the 174 papers of 2011 to 2015. Between the same two periods, all the animal research papers that mention any of the 90 tests we count grew more slowly, to 1.2 times as many.

264 animal research papers from 2021 to 2025 mentioned carotid artery occlusion (BCCAO, 2VO) and a test
1.5 times as many papers as in 2011 to 2015
70% of these papers mention the Morris water maze
39% of the 679 animal research papers from 2021 to 2025 that mention carotid artery occlusion (BCCAO, 2VO) also mention a test

The tests mentioned with carotid artery occlusion (BCCAO, 2VO)

The Morris water maze appears in 70% of these papers and in 17% of all 32,277 papers that mention a test. That makes it 4.2 times as common in this research. Each bar is one test, with how many of the 264 papers from 2021 to 2025 mention it, and what share that is. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

185 papers 70%
38 papers 14%
23 papers 9%
19 papers 7%
10 papers 4%
9 papers 3%
7 papers 3%
7 papers 3%
7 papers 3%
5 papers 2%
All 36 tests these papers mention
Papers from 2021 to 2025 that mention carotid artery occlusion (BCCAO, 2VO) and each test
TestPapersShare of the 264 papers
Morris water maze18570%
Novel object recognition5922%
Y-maze3814%
Open field239%
Passive avoidance197%
Rotarod104%
Barnes maze93%
Radial arm maze73%
Wheel running73%
Treadmill running73%
Grip strength73%
Elevated plus maze62%
Forced swim test52%
Tail suspension test52%
Sucrose preference test52%
Adhesive removal test42%
Ladder rung walking31%
Wire hang and inverted grid21%
Pole test21%
Light-dark box21%
Fear conditioning21%
Grid walking (foot fault)21%
Beam walking21%
Active avoidance (shuttle box)21%
Elevated zero maze1under 1%
Social interaction test1under 1%
T-maze1under 1%
Step-down avoidance1under 1%
Von Frey test1under 1%
Novelty-suppressed feeding1under 1%
Nest building1under 1%
Olfactory tests1under 1%
Negative geotaxis and climbing assays1under 1%
Radial arm water maze1under 1%
Gait analysis1under 1%
Object location test1under 1%

Tests named in 30 or more of these papers link to a page on that test with carotid artery occlusion (BCCAO, 2VO). To count the papers that mention two or more tests together, use the test battery tool.

Papers by year

Animal research papers that mention carotid artery occlusion (BCCAO, 2VO) and a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20014
20028
20031
20042
20058
200612
200712
200816
200912
201021
201121
201229
201332
201441
201551
201636
201744
201853
201945
202059
202152
202256
202347
202451
202558
2026 (part year)59

Disease models in papers that mention carotid artery occlusion (BCCAO, 2VO)

Each bar is one disease model, with how many of the 264 papers from 2021 to 2025 are tagged with it, and what share that is. The model comes from the paper's MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. A paper without MeSH terms gets its model from PubTator 3, NCBI's text-mining service, if PubTator 3 finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

Which species the papers used

Each bar is a share of the 264 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Rat
180 papers 68%
Mouse
92 papers 35%
Other animals
3 papers 1%
Zebrafish
1 paper under 1%

“Other animals” counts papers that use none of the species this chart names.

NIH funding

15 of the 264 papers (6%) had NIH funding. NINDS, the National Institute of Neurological Disorders and Stroke, funded the most, 13 of them. A paper counts as NIH-funded when its PubMed record lists an NIH grant, or when NIH RePORTER links it to an NIH project.

NIH-funded papers by institute

NINDSNational Institute of Neurological Disorders and Stroke
13 papers 87%
NIANational Institute on Aging
7 papers 47%
NIGMSNational Institute of General Medical Sciences
2 papers 13%
NHLBINational Heart, Lung, and Blood Institute
1 paper 7%
NIEHSNational Institute of Environmental Health Sciences
1 paper 7%
NICHDEunice Kennedy Shriver National Institute of Child Health and Human Development
1 paper 7%

Each share is of the NIH-funded papers. A paper with grants from two institutes counts under both.

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention carotid artery occlusion (BCCAO, 2VO) and a behavioral test and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils.

    Life Sci, 2021. 159 citations.

  2. High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner.

    J Neuroinflammation, 2022. 113 citations.

  3. Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.

    Phytomedicine, 2023. 76 citations.

  4. Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice.

    J Ginseng Res, 2022. 71 citations.

  5. Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance.

    J Neuroinflammation, 2022. 68 citations.

How we counted

A paper counts here when it is animal research and its title or abstract mentions carotid artery occlusion (BCCAO, 2VO) and at least one of the 90 behavioral tests. A count is a number of papers, not of experiments, labs or animals. A paper that mentions carotid artery occlusion (BCCAO, 2VO) only in its methods is missed, so the count runs low.

A paper is animal research when its MeSH terms name an animal species. If they name none, NCBI's text-mining service PubTator 3 has to find one in the title or abstract. Papers on animals other than mice, rats, zebrafish, flies and primates count only when they also mention a test. Many of them study people or use the same words for something else.

The search terms for carotid artery occlusion (BCCAO, 2VO) are in the download Animal models and brain techniques. The counts in the chart of tests are in Tests mentioned with each model or technique. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More animal models

Each animal model with 100 or more papers from 2021 to 2025 that mention a test has a page. These are the others, each with that count.

How to cite

APA

ConductScience. (2026, November 13). Behavioral tests with carotid artery occlusion (BCCAO, 2VO) [Data set]. https://conductscience.com/resources/data/animal-models/carotid-occlusion

BibTeX

@misc{conductscience_carotid_occlusion_2026,
  author = {{ConductScience}},
  title = {Behavioral tests with carotid artery occlusion (BCCAO, 2VO)},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/animal-models/carotid-occlusion},
  note = {Data set, released November 13, 2026},
}

Equipment in our store

For studies with carotid artery occlusion (BCCAO, 2VO), our store sells:

Apparatus for the tests

Our store sells apparatus for all the 10 tests these papers mention most.

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