Species Hub/African Clawed Frog Tadpole/Optokinetic Response (OKR)
Primary Assay — African Clawed Frog Tadpole

Optokinetic Response (OKR)

Xenopus laevis

Quantification of visually driven eye movements in response to moving gratings. OKR gain and contrast sensitivity provide non-invasive readouts of visual system function.

African Clawed Frog Tadpole — Optokinetic Response (OKR)

Measured Parameters

Every parameter is automatically tracked frame-by-frame in the ConductVision pipeline for Xenopus laevis.

ParameterUnitDescription
Slow-phase eye velocity°/sTracking speed
OKR gainratioEye velocity / stimulus velocity
Contrast threshold%Minimum contrast for response

Citations for Optokinetic Response (OKR)

  1. Gravot CM, et al. (2017). Visual scene parameters influence optokinetic reflex performance in Xenopus laevis tadpoles. J Exp Biol, 220(22), 4213-4224. PMID: 29141881
  2. Viczian AS, et al. (2014). A simple behavioral assay for testing visual function in Xenopus laevis. J Vis Exp, (88), 51726. PMID: 24962702

Hardware for African Clawed Frog Tadpole Research

Tadpole Observation Chamber

Swimming behavior recording

Vibration Stimulus Platform

Startle/escape triggering

Looming Stimulus Display

Visual avoidance testing

Flow Chamber

Rheotaxis assays

Infrared Camera System

Dark-adapted recording

Run Optokinetic Response (OKR) on ConductVision

Our team will configure the protocol, camera rig, and analysis pipeline for your african clawed frog tadpole facility.