Primary Assay — African Clawed Frog Tadpole
Swimming Locomotion (CPG)
Xenopus laevis
Central pattern generator-driven swimming analysis measuring cycle frequency, bout duration, and tail beat amplitude. These parameters provide direct readouts of spinal locomotor circuit maturation.
Quantitative Output
Measured Parameters
Every parameter is automatically tracked frame-by-frame in the ConductVision pipeline for Xenopus laevis.
| Parameter | Unit | Description |
|---|---|---|
| Cycle frequency | Hz | Swimming rhythm |
| Swim episode duration | s | Bout length |
| Tail beat amplitude | μm | Wave magnitude |
| Inter-episode interval | s | Rest between bouts |
References
Citations for Swimming Locomotion (CPG)
- Picton LD, et al. (2018). Control of Xenopus Tadpole Locomotion via Selective Expression of Ih in Excitatory Interneurons. Curr Biol, 28(24), 4134-4142. PMID: 30503615
- Sillar KT, et al. (1998). Development and aminergic neuromodulation of a spinal locomotor network controlling swimming in Xenopus larvae. Ann N Y Acad Sci, 860, 318-332. PMID: 9928322
Compatible Equipment
Hardware for African Clawed Frog Tadpole Research
Tadpole Observation Chamber
Swimming behavior recording
Vibration Stimulus Platform
Startle/escape triggering
Looming Stimulus Display
Visual avoidance testing
Flow Chamber
Rheotaxis assays
Infrared Camera System
Dark-adapted recording
Related Assays
Other African Clawed Frog Tadpole Primary Assays
02
Startle / Escape Response (Mauthner-cell mediated)
Xenopus laevis
High-speed analysis of the C-start escape response mediated by Mauthner cells. This reflex provides a direct readout of …
02
Visual Avoidance (Looming Stimulus)
Xenopus laevis
Looming stimulus avoidance assay testing visual processing and collision avoidance circuitry. Tadpoles respond to expand…
02
Optokinetic Response (OKR)
Xenopus laevis
Quantification of visually driven eye movements in response to moving gratings. OKR gain and contrast sensitivity provid…
Run Swimming Locomotion (CPG) on ConductVision
Our team will configure the protocol, camera rig, and analysis pipeline for your african clawed frog tadpole facility.
