Vertical Pressure Autoclave
50L vertical pressure autoclave with 0.23 MPa working pressure, 105-136°C temperature range, and integrated printer for laboratory sterilization applications.
Louise Corscadden, PhD
Director of Science · ConductScience
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Key Specifications
Full details →- Model fit
- Configured during quote
- SKU family
- BIO-0146
- Sizing
- 107.0 x 64.0 x 55.0 cm
- Ordering
- Online checkout and quote request available
- Category
- Autoclaves
- Build notes
- S30408
The Vertical Pressure Autoclave (BIO-0146) is a 50L capacity steam sterilization system designed for laboratory and clinical applications requiring reliable instrument sterilization. The unit operates at working pressures up to 0.23 MPa and temperatures from 105°C to 136°C, with 0.1°C temperature precision for consistent sterilization cycles. The autoclave features a vertical chamber design fabricated from S30408 stainless steel, providing corrosion resistance and durability in high-temperature, high-pressure environments.
The system includes integrated data recording capabilities with a built-in printer for cycle documentation and traceability. The compact vertical configuration (chamber dimensions φ386×490mm) maximizes sterilization capacity while minimizing laboratory footprint. Standard accessories include a mesh bottom basket (φ365×265mm) for instrument organization during sterilization cycles. The unit operates at low noise levels (≤65dB) suitable for laboratory environments and includes altitude considerations for installations between 1000-2700 meters.
How It Works
The autoclave employs moist heat sterilization through pressurized steam to achieve microbial kill. Steam under pressure allows temperatures above 100°C at atmospheric conditions, with the combination of elevated temperature, pressure, and moisture providing effective destruction of vegetative bacteria, spores, viruses, and fungi. The 0.23 MPa working pressure enables steam temperatures of 105-136°C, which penetrates materials and denatures proteins essential for microbial survival.
The vertical chamber design promotes efficient steam circulation and heat distribution throughout the load. Steam enters the chamber and displaces air, creating uniform temperature conditions measured with 0.1°C precision. The S30408 stainless steel construction resists corrosion from steam and cleaning agents while maintaining structural integrity under repeated pressure cycling. The integrated printer documents time, temperature, and pressure parameters for each sterilization cycle, providing traceability records required in regulated laboratories.
Features & Benefits
Automation Level
- semi-automated
Designed Pressure
- 0.28MPa
Working Pressure
- 0.23MPa
Designed Temp.
- 150℃
Working Temp.
- 105°C~136°C
Temp. Precision
- 0.1℃
Chamber Material
- S30408
Chamber Size
- φ386*490mm
Basket
- φ365*265mm, 1pc
Noise
- ≤65dB
Altitude
- ≤2700m, please make a note when placing an order between 1000~2700 meters
Standard Accessories
- Printer, mesh bottom basket
Optional Accessories
- Air compressor
Consumption
- 5.5KW
Brand
- ConductScience
Research Domain
- Analytical Chemistry
- Cell Biology
- Clinical Diagnostics
- Environmental Monitoring
- Microbiology
- Pharmaceutical QC
Capacity
- 50L
Weight
- 127.0 kg
Dimensions
- L: 107.0 mm
- W: 64.0 mm
- H: 55.0 mm
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Chamber Capacity | 50L vertical chamber | Entry-level models often offer 15-25L capacity | Reduces sterilization frequency and increases laboratory productivity through larger batch processing |
| Temperature Precision | 0.1°C temperature control | Basic models typically provide ±1-2°C accuracy | Ensures consistent sterilization conditions for validated processes and regulatory documentation |
| Integrated Documentation | Built-in printer for cycle records | Many models lack automatic documentation features | Eliminates manual record-keeping and provides traceable sterilization documentation for quality systems |
| Chamber Material | S30408 stainless steel construction | Standard models often use lower-grade stainless steel | Provides superior corrosion resistance and longevity in demanding laboratory environments |
| Working Pressure | 0.23 MPa (33.4 psi) working pressure | Varies by model and capacity | Enables high-temperature sterilization cycles up to 136°C for effective spore destruction |
| Noise Level | ≤65dB operation | Many autoclaves operate at higher noise levels | Maintains quiet laboratory environment suitable for precision work and staff comfort |
This autoclave combines substantial 50L capacity with precision temperature control and integrated documentation in a vertical design that maximizes laboratory space efficiency. The S30408 stainless steel construction and quiet operation provide durability and user comfort for demanding research environments.
Practical Tips
Verify temperature accuracy using Type T thermocouples placed at multiple chamber locations during empty and loaded test cycles.
Why: Ensures uniform heat distribution and validates sterilization effectiveness throughout the chamber volume.
Perform weekly chamber cleaning with enzymatic detergent followed by rinse cycles to remove protein residues and mineral deposits.
Why: Prevents buildup that can interfere with steam circulation and cause corrosion of chamber surfaces.
Leave space between items in the mesh basket and avoid overloading to ensure adequate steam penetration to all surfaces.
Why: Steam must contact all surfaces directly for effective sterilization, and overcrowding creates steam shadows that compromise sterility assurance.
Replace printer paper regularly and store printed records in controlled environment to prevent fading of thermal printouts.
Why: Thermal printing can fade over time, potentially compromising long-term traceability records required for regulatory compliance.
If temperature does not reach setpoint, check steam generator water level and descale heating elements if mineral buildup is suspected.
Why: Scale formation reduces heat transfer efficiency and can cause temperature control problems or heating element failure.
Allow complete pressure release and cooling before opening chamber door, and use protective equipment when handling hot items.
Why: Residual pressure and high temperatures can cause serious injury, and superheated materials may not appear hot despite dangerous temperatures.
Use biological indicators containing Geobacillus stearothermophilus spores monthly to verify sterilization effectiveness.
Why: Biological indicators provide the most stringent test of sterilization efficacy and are required for process validation in regulated environments.
Inspect door gaskets monthly for cracks, cuts, or hardening that could compromise pressure seal integrity.
Why: Damaged gaskets allow pressure loss that prevents proper sterilization temperatures and creates safety hazards from steam leaks.
Setup Guide
What’s in the Box
- Vertical pressure autoclave main unit
- Integrated printer system
- Mesh bottom basket (φ365×265mm)
- Power cable
- User manual and documentation
- Installation hardware (typical)
- Calibration certificate (typical)
Warranty
ConductScience provides a standard one-year manufacturer warranty covering parts and labor, with technical support available for installation guidance and operational troubleshooting.
Compliance
What sterilization cycles are appropriate for different laboratory materials?
Cycle selection depends on material type and contamination risk. Unwrapped instruments typically require 15-20 minutes at 121°C, while wrapped packs or porous materials may need 30-45 minutes. Heat-sensitive plastics should be evaluated for temperature compatibility up to 136°C maximum.
How frequently should temperature and pressure calibration be verified?
Temperature calibration should be verified quarterly using certified reference thermometers, while pressure calibration requires annual verification with certified pressure gauges. More frequent verification may be required in validated pharmaceutical or clinical environments.
Can this autoclave process liquid media and what precautions are needed?
Yes, liquid sterilization is supported with appropriate containers and venting. Use slow cooling cycles to prevent violent boiling, ensure containers are no more than 75% full, and use vented caps or loose closures to prevent container damage from pressure differentials.
What maintenance procedures are required for reliable operation?
Weekly cleaning of chamber and drain with appropriate detergents, monthly inspection of door seals and safety valves, and quarterly descaling based on water quality. Replace printer paper and inspect electrical connections regularly.
How does the integrated printer support quality system requirements?
The printer automatically documents cycle time, temperature, pressure, and date for each sterilization run. These records provide traceability documentation required for ISO 15189, CAP, and pharmaceutical GMP compliance programs.
What are the electrical and utility requirements for installation?
Requires dedicated electrical supply for 5.5kW consumption, water supply for steam generation, and drain connection for condensate removal. Consult local electrical codes for proper circuit sizing and grounding requirements.
How does chamber capacity compare to horizontal bench-top autoclaves?
The 50L vertical design maximizes volume utilization compared to horizontal models of similar footprint. The φ386×490mm chamber accommodates tall containers and long instruments that may not fit in horizontal chambers with height restrictions.
What considerations apply for high-altitude installations?
Installations between 1000-2700m altitude require notation during ordering for proper pressure and temperature calibration adjustments. Above 2700m altitude is not supported due to reduced atmospheric pressure effects on steam generation.
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