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Five Choice Serial Reaction Time Task (5CSRTT)

See more by: MazeEngineers

Price range: $5,990.00 through $6,990.00

10% off with your subscription Membership
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 / Availability: In Stock / Delivery Info ⓘ

Description

The 5-Choice Serial Reaction Time task or 5CSRTT was developed by Robbins et al  (Robbins et al., 2002) to study behavioral traits associated with attention deficit hyperactivity disorder (ADHD) such as attention and impulse control.

The 5CSRTT apparatus consists of an operant conditioning chamber with 2 Plexiglas sidewalls; the aluminum front wall is rounded and contains five nose poke apertures (2.5 x 2.2 x 2.2 cm each, 2 cm above the floor)

Each apparatus you purchase from ConductScience comes with a stimulus LED light as well as an infrared nose poke sensor.

A stainless steel back wall has a food cachet installed which provides food pellets from the pellet dispenser. Infrared sensor and an LED signal light. included

The shocker floor grid allows for punishment in the experiment. The removable feces and urine tray below this grid allow for easy cleaning.

Meet the producer

Producer: MazeEngineers

MazeEngineers offers custom-built behavioral mazes at no extra cost—designed to fit your exact research needs. Eliminate reproducibility issues from poor sizing or lingering scent cues with precision-engineered, modular, and smart mazes that adapt in real time to animal behavior. Publish new protocols, run adaptive experiments, and push the boundaries of behavioral science.

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Description

Specifications

Mouse 5CSRTT

Rat CSRTT

Aperature Dimension: 1.3 x 1.2 x 1.2 cm width x height x depth; 1 cm above the floor

Aperture dimension: 2.8 x 2.8 x 2.2 cm width x height x depth; 2 cm above the floor

Interior Dimension: 20 x 20 x 25 cm

Interior Dimension: 30 x 25 x 30 cm (width x depth x height)

5 nose poke apertures

5 nose poke apertures

LED visual stimuli (IR Based)

LED visual stimuli (IR Based)

Incandescent house light

Incandescent house light

Food magazine

Food magazine

Shock Grid

Shock Grid

Pellet Dispenser

Pellet Dispenser

Feces and urine tray; removable

Feces and urine tray; removable

Aluminum back wall

Aluminum back wall

Isolation cubicle not included

Isolation cubicle not included

Features

Conductor Software

  • Our 5CSRTT is compatible with 2 software options to control the system and configure protocols
  • Our Conductor software for controlling the system alone (no video tracking/analysis included)
  • Our complete tracking and analysis package ConductVision.

Pellet Dispenser

  • Uses Maze Engineers’ Pellet Dispenser. The user configures what condition(s) a pellet is dispensed. The software captures and reports nose poke events on pellets.
  • Learn more about our Pellet Dispenser.

Shock Stimulus

  • Shock generator as a separate component outside the Isolation Cubicle
  • Removable grid – mouse rod diameter 3mm, spacing 5 mm. Rat rod diameter 6mm, spacing 10mm
  • Current control can be controlled programmatically or manually
  • Start or stop is controlled programmatically or manually
  • Shock: Constant current – from 0.1 to 4.0 mA in 0.1 mA steps

Light Stimulus

  • Sound-proof insulation material
  • Cubicle material
  • Air circulation: one fan on the back wall

Isolation Cubicle

  • The light volume is specified by user with range 0-100 with step 1. The light intensity in the chambers is measured by Lux. The relationship between light level and intensity is calibrated.
  • Optional: configurable color lights

Introduction

The 5CSRTT (5-Choice Serial Reaction Time Test) Apparatus is used to assess attention and impulse behaviors processes in rodents (Robbins et al., 2002). It consists of an operant test chamber containing a curved wall with five nose poke apertures. A stimulus LED light is present in each aperture to signal food retrieval. Food can be retrieved from a food cachet connected to a food dispenser on the opposite wall of the chamber. During the task, the subject must pay attention to the apertures to detect the signal and respond correctly to obtain the food reward within a limited time window. If the subject responds incorrectly by an error of commission (responding in a hole where the signal is not presented), error of omission (failing to respond to the signal within the prescribed time limit), or premature responses (responding before the signal presentation), it is punished by a time-out period, which is a brief period of darkness. In addition, the 5CSRTT Apparatus also contains a shocker floor grid to provide punishment. 

Impaired attention and impulsivity are characteristics of many mental health disorders (Robbins et al., 2002Egeland, 2007). The 5CSRTT Apparatus can effectively be used to examine impaired attention and impulse control in rodents, which can be used as a model to understand the neurobiology of these psychiatric illnesses. During testing, the subject is placed in the apparatus and required to withhold poking its nose in any of the apertures until the appearance of the signal. Therefore, motor impulsivity can be assessed from the number of premature responses before presenting the visual signal. Additionally, perseverative responses, another form of inhibitory deficit, can also be assessed in which the subjects continue to respond at the response apertures even after signalled food presentation. The 5CRSTT Apparatus measures sustained attention by observing the subject’s ability to complete the task with the visual cue varying in location over a large number of trials. Moreover, varying the visual cue in location, duration, and timing (pre-cue delay) across trials also enables independent assessment of impulsivity. Other aspects of attention, such as selective attention, can also be examined on the 5CSRTT Apparatus by presenting distracting stimuli during the interval between trial onset and visual cue presentation. 

The 5CSRTT Apparatus can also be used to investigate the effect of selective lesions, pharmacological manipulations, and diseases and disorders on attention and impulsivity in rodents. 

Other apparatuses used to study attention and impulsivity in rodents:

Additional information

Dimensions N/A
Species

Mouse, Rat

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