Human Sex Chromosomes and X-inactivation

Introduction Chromosomes are thread-like structures, located in the nucleus, which carry hereditary information in the form of genes. Structurally, it is composed of ‘packaging proteins and DNA molecules’, and it is represented in different shapes and numbers which vary among different living organisms. For example, bacteria have circular chromosomes, whereas organisms like humans and other […]

Estimating the Chiasma Frequency in Diplotene-Diakinesis Stage

Reference to this article: ConductScience, Estimating the Chiasma Frequency in Diplotene-Diakinesis Stage (2019). doi.org/10.55157/CS20200925 Introduction Chiasma is the point of crossing over or site where the exchange of genetic material takes place between two homologous, non-sister chromatids. The crossover occurs in the pachytene stage, however, it is observed in the diplotene stage of meiosis-I[2]. The […]

sgRNA construction and design

Clustered regularly interspaced short palindromic repeats (CRISPR) technology is a rapid, cheap, and efficient tool to edit genomes at a precise location. CRISPR technology has now been reduced to just two components: Endonuclease and g RNA. Endonuclease makes an incision at the target DNA molecule to be edited, and gRNA is a single-stranded synthetic 20 […]

Agarose Gel Electrophoresis

Need Electrophoresis Equipment for your research? Click here   Agarose gel electrophoresis is a type of gel electrophoresis that uses agarose, a natural polysaccharide isolated from red seaweed agar, as a matrix to separate molecules or components based on their size. It is an uncomplicated, yet versatile analytical method that can accommodate both research and […]

Pre-market Approval for Medical Devices

Need Digital Health Services for your research? Click here Pre-market Approval for Medical Devices: Introduction The US is the largest market for medical devices, worth approximately $156 billion (as of 2017), and is expected to reach $208 billion by 2023. Given these numbers, it’s no surprise that high-risk medical devices must undergo strict regulatory and […]

Science and Foreign Affairs: A Global Consolidation for a Better World

Science and Foreign Affairs: Introduction From climate change policies to pandemic preparedness plans, foreign relations impact people on an individual, national, and global level. The world of international affairs is, in fact, a mixture of politics, culture, economics, and innovations, with science and technology being two of the main factors in improving multinational relations.  Whether […]

Gel Electrophoresis

Need Electrophoresis Equipment for your research? Click here Gel electrophoresis is a type of electrophoresis that separates molecules or components based on their size or conformation in a matrix made from gel-forming substances. Since its conception, gel electrophoresis has been modified, in terms of gel types, composition, and the set-up of the system to accommodate […]

Introduction to Electrophoresis

Need Electrophoresis Equipment for your research? Click here   Electrophoresis is a technique that separates molecules in their liquid state, based on their ability to move in an electric field. The various forms and types of electrophoresis have become the leading methods of the analysis of biomolecules in biochemistry and molecular biology, including genetic materials […]

Can You Divide a Strand of Hair? The Ultramicrotome

Need Microtomes for your studies? Click here As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases   What is the Ultramicrotome? Microtomes are specifically designed devices for the cutting of extremely thin sections from samples, for the study of their microscopic composition. Samples can be of biological origins, such as tissues, cells, and […]