The Heat Maze Experience
Advancing Spatial Learning in Drosophila
The Heat Maze is a cutting-edge behavioral tool designed to study spatial learning and cognition in Drosophila melanogaster. By combining heat-based aversive stimuli with visual cues, it reveals how flies navigate, remember, and adapt across trials.
Unveiling Spatial Learning
Insights from the Heat Maze
Metrics ConductVision measures for the Heat Maze
Latency to First Safe Zone Contact
Measures how quickly flies reach the safe zone. Reduced latency over trials indicates improved spatial learning.
Search Strategy Progression
Tracks the transition from random to directed search patterns, revealing learning speed and strategy development.
Time Spent & Distance Traveled
Monitors time in the safe zone and distance traveled outside it. Efficient navigation increases time in safety and reduces unnecessary movement.
Search Strategies
- Thigmotaxis: The subject stays close to the arena wallātypically associated with anxiety-related behavior.
- Random Search: The subject explores the arena in an unstructured manner without targeting specific cues.
- Scanning: The fly explores only the central area, where visual cues are placed. This is a non-spatial search strategy.
- Chaining: The subject searches within the annulus zone (approximately 3 cm from the safe zone), representing another non-spatial strategy.
- Directed Search: The fly searches within a defined corridor (~6 cm) between the starting point and the safe zone.
- Focal Search: The search is concentrated in the immediate area around the safe zone, with a very short mean distance to the zone (<3 cm).
- Direct Search: The subject moves directly to the safe zone, indicating the most efficient and learned strategy.
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