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Learned Helplessness System

An Essential Tool for Depression Research

The Learned Helplessness Paradigm is a widely recognized animal model of depression, originally described by Overmier and Seligman (1967). This paradigm demonstrates how exposure to inescapable shocks can result in deficits in emotional expression, associative learning, and behavioral coping.

Key Results Metrics

Analyzing Behavioral Coping and Learned Helplessness

The Learned Helplessness System provides critical metrics to assess behavioral coping, stress responses, and depressive-like symptoms in animal models. These measurements are invaluable for understanding the effects of stress and antidepressant therapies in preclinical research.

Test Duration

Tracks the duration of the test session, indicating overall exposure time and behavioral performance.

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Escape Latency

Measures the time taken by the subject to escape the aversive stimulus, reflecting learning and coping mechanisms.

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Number of Failures

Counts the failures to escape the shock, serving as a key indicator of helplessness and depressive-like behavior.

Comprehensive Behavioral Analysis

A validated model for studying depressive-like behaviors, featuring precise tools for evaluating emotional, cognitive, and stress-coping responses in animal research.

Dynamic Stress-Induced Testing

Subjects are exposed to controllable or inescapable shocks, enabling studies of active and passive avoidance, resilience, and behavioral adaptation.

Automated Behavioral Analysis

Records key behavioral metrics, such as escape latency and avoidance patterns, providing deep insights into stress responses and coping mechanisms.

Comprehensive Experiment Reporting

Automatically logs key data, generating detailed reports with visual metrics for effortless analysis and comparison across trials.

Key Features

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High-Precision Shock Grid Integration

Smooth DC shock delivery with adjustable current levels (0–4 mA) for precise control and accuracy in experiments.

Shock Grid Integration:

Shock Grid Integration: Programmatically or manually controlled current levels (0.1–4.0 mA).

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Robust and Durable Construction

Stainless steel and acrylic design ensures long-lasting reliability and ease of cleaning between experiments.

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Interchangeable Plating System

Fully customizable contextual plates with a range of colors and patterns for tailored visual cues.

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Customizable Chamber Dimensions

Adjustable to accommodate mice or rats, with configurations suited to different experimental needs.

Specifications

Chamber Dimensions:

20 cm x 20 cm x 28 cm (mice) and 22 cm x 22 cm x 20 cm (rats).

Shock Grid Spacing:

5 mm for mice, 6 mm for rats, ensuring accurate stimulus delivery.

Shock Current Range:

Adjustable from 0.1 mA to 4.0 mA, with smooth DC shock delivery for precision.

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Construction Material:

Durable stainless steel with optional Plexiglas walls for enhanced visibility.

Software Compatibility:

Fully integrated with ConductVision, Noldus Ethovision XT, and ANY-Maze for advanced tracking and analysis.

Automated Data Collection and Reporting

The Learned Helplessness System streamlines data collection and analysis, providing comprehensive reports with behavioral metrics, graphical visualizations, and statistical insights. This enhances research efficiency and improves interpretation of experimental results.

 

Tools for Advanced Behavioral Studies

ConductVision provides cutting-edge applications, mazes, and equipment for precise behavioral research. Our software automates tests, while our range of tools ensures researchers have what they need for seamless experimentation. 

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