Electrophysiology Chambers: How To Examine Tissue Slices
What Are Electrophysiology Chambers? Electrophysiology chambers are designed to study tissue electrophysiology in preclinical research. These chambers can be used for tissue slices in neuropharmacological and toxicological animal models in preclinical research, especially in rodents like rats and guinea pigs. Electrophysiological recordings can be taken simultaneously from tissue slices using electrophysiology chambers, which allows researchers […]
Vibrating Microtomes: What They Are & Their Applications
What are Vibrating Microtomes? Before the tissue slicers, scientists had to manually cut biological materials with their tools, which required meticulous work for great precision. With the invention of the tissue slicers, mainly the microtomes (from the Greek mikros, meaning “small,” and temnein, meaning “to cut”), biological specimens such as sensitive tissues, brain slices, and […]
Isoflurane For Animal Anesthesia: How to Safely Use
What Is Isoflurane? Isoflurane, also known by the brand names, Forane and Terrel, is an inhalation anesthetic used in animal research to induce general anesthesia.[1] Figure: The structure of Isoflurane. Inhalation anesthetics are medicines or anesthetic agents that induce and maintain general anesthesia via inhalation through a mask. General anesthesia is a combination of medicines […]
Is Sevoflurane A Better Anesthetic Agent?
What is Sevoflurane? Sevoflurane is a volatile, non-flammable, and highly fluorinated methyl isopropyl ether anesthetic agent used to induce and maintain general anesthesia in patients or lab animals.[1] Figure: Chemical structure of Sevoflurane.[1] General anesthesia is a combination of drugs used during surgeries, medical procedures, or dissection of live animals in lab experiments to create […]
What Are the Different Types of Nucleic Acids Extraction Methods?
Nucleic acids such as deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are macromolecules that carry genetic information in organisms. DNA consists of double nucleotide strands that are complementary to one another. The sequence of nucleotides signifies genetic elements, including genes, transcription factors, and regulators. RNA only has one nucleotide strand transcribed from one DNA strand. […]
Autoclave Sterilizers 101: How They Work Plus Safety Tips
Reference to this article: ConductScience, Autoclave Sterilizers 101: How They Work Plus Safety Tips (2022). doi.org/10.55157/CS20220717 What Is an Autoclave? An autoclave is a machine used in industrial and scientific labs to sterilize or decontaminate items.[1] It applies particular heat under pressure to the machineās chamber to kill harmful pathogens, such as bacteria, fungi, spores, […]
What Is Optogenetics and How Does It Work?
Reference to this article: ConductScience, What Is Optogenetics and How Does It Work? (2022). doi.org/10.55157/CS20220704 Need optogenetic devices for your lab? Click here What Is Optogenetics? Optogenetics is a method of controlling and monitoring the functions of cells, tissues, and organisms by combining specialized optical systems and genetic engineering technologies.[1] It is now considered a […]
Ultimate Guide to Automated Cell Counter: Plus Purchasing Tips
Reference to this article: ConductScience, Ultimate Guide to Automated Cell Counter: Plus Purchasing Tips (2022). doi.org/10.55157/CS20220614 Introduction Cell counting is routinely performed in life science research labs and medical diagnosis and treatment. There are many ways to count cells in labs, which do not require special equipment. However, the use of equipment and instruments increases […]
The Cryostat-Microtome
Need Microtomes for your studies? Click here A Glimpse into the History of a Cryostat A Cryostat is a versatile and high-quality machine that generates low temperatures for tissue sectioning. The word āCryostatā originates from two separate Greek words āKryosā, meaning cold, and āstatā, meaning stable. Sir James Dewar, a Scottish Physicist, and Chemist are […]