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Four mountains test

See more by: Simian Labs

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Description

Examine the relationship between allocentric and orientation spatial memory and the risk of cognitive impairment or dementia by studying associated brain areas in environments that are more natural and human-like. This approach contrasts with traditional methods such as the VR Morris Water Maze or other laboratory-based maze tests, providing a more realistic assessment of how these cognitive functions operate in everyday settings. By utilizing real-world scenarios, researchers aim to gain a deeper understanding of the brain’s role in spatial memory and its impact on dementia, potentially leading to more effective diagnostic and therapeutic strategies.

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Producer: Simian Labs

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Description

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Specifications

3.5 × 3.5 m space

Tracked boundary by 30 cm

Alarm and visual warning if the user moves beyond the boundary.

“‘L’-shaped outward path to three different locations

Each marked by inverted cones at head height numbered one two and three

Parameters to measure

Protocols

9 trials conducted within each of the three environments, totalling, 27 trials per participant.

Path integration

The return path conditions were altered to three different environments: condition A, no environmental change  (Fig. 1D), condition B, removal of boundary cues (Fig. 1E); and condition C, removal of surface detail (Fig. 1F).

Each return condition was presented three times per environment, with return conditions presented pseudo-randomly in each environment.

20 seconds of habituation

The user is asked to walk in an ‘L’-shaped outward path to three different locations. Inverted cones 2 and 3 disappear once the user reaches them.

Upon reaching cone 3, a message is projected onto the scene asking the user to talk back to location 1 using their memory via a round-trip path.

An auditory stimulus and the appearance of a cone alert participants to walk to the next cone location.

The user presses the controller trigger when he believes he has reached the estimated location of cone 1, which ends the test.

And at the end, the following results are obtained:

References

Vr version: 

Howett, D., Castegnaro, A., Krzywicka, K., Hagman, J., Marchment, D., Henson, R., Rio, M., King, J. A., Burgess, N., & Chan, D. (2019). Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. Brain, 142(6), 1751-1766. https://doi.org/10.1093/brain/awz116

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