Research data · Disease model and test

Forced swim test in depression research

From 2021 to 2025, 1,822 animal research papers on depression mentioned the forced swim test in their title or abstract.

That is 1.4 times the 1,300 papers of 2011 to 2015. Between the same two periods, the papers on depression that mention any of the 90 tests we count grew faster, to 1.5 times as many.

1,822 papers on depression from 2021 to 2025 mentioned the forced swim test
64% of the papers on depression that mention any test mention the forced swim test
61% of the papers that mention the forced swim test are on depression
1.4 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on depression that mention the forced swim test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200135
200256
200350
200459
200564
200682
2007107
2008165
2009144
2010180
2011219
2012224
2013237
2014313
2015307
2016359
2017375
2018389
2019399
2020383
2021389
2022348
2023286
2024372
2025427
2026 (part year)381

Papers on depression that mention the forced swim test fell from 389 in 2021 to 286 in 2023, then rose to 427 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 1,822 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
1,104 papers 61%
Rat
758 papers 42%
Other animals
24 papers 1%
Zebrafish
2 papers under 1%
Fruit fly
2 papers under 1%

“Other animals” counts papers that use none of the species this chart names.

Tests mentioned alongside the forced swim test

Each bar is one test, with how many of the 1,822 papers also mention it, and what share that is. Of these papers, 285 (16%) mention no other test.

The 12 tests these papers mention most

700 papers 38%
633 papers 35%
394 papers 22%
96 papers 5%
78 papers 4%
46 papers 3%
41 papers 2%
34 papers 2%

Which papers count

A paper counts here when it is animal research, mentions the forced swim test in its title or abstract, and studies depression.

We tell whether a paper studies depression from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on depression research names the subject headings we count as depression. Download the test list for the search terms we used for the forced swim test, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on the forced swim test counts all the papers that mention it, whatever they study. The page on depression research ranks the tests by their papers on depression.

How to cite

APA

ConductScience. (2026, November 10). Forced swim test in depression research [Data set]. https://conductscience.com/data/behavioral-tests/models/depression/forced-swim-test

BibTeX

@misc{conductscience_depression_forced_swim_test_2026,
  author = {{ConductScience}},
  title = {Forced swim test in depression research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/depression/forced-swim-test},
  note = {Data set, released November 10, 2026},
}

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