Research data · Disease model and test

Sucrose preference test in depression research

From 2021 to 2025, 1,102 animal research papers on depression mentioned the sucrose preference test in their title or abstract.

That is 3.3 times the 333 papers of 2011 to 2015. Between the same two periods, the papers on depression that mention any of the 90 tests we count grew more slowly, to 1.5 times as many.

1,102 papers on depression from 2021 to 2025 mentioned the sucrose preference test
39% of the papers on depression that mention any test mention the sucrose preference test
72% of the papers that mention the sucrose preference test are on depression
3.3 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on depression that mention the sucrose preference test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20012
20023
20031
20043
20052
20067
20078
200821
200918
201022
201142
201239
201361
201487
2015104
2016106
2017134
2018154
2019194
2020178
2021214
2022213
2023174
2024212
2025289
2026 (part year)257

Papers on depression that mention the sucrose preference test fell from 214 in 2021 to 174 in 2023, then rose to 289 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 1,102 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
593 papers 54%
Rat
521 papers 47%
Other animals
14 papers 1%
Zebrafish
1 paper under 1%
Fruit fly
1 paper under 1%

“Other animals” counts papers that use none of the species this chart names.

Tests mentioned alongside the sucrose preference test

Each bar is one test, with how many of the 1,102 papers also mention it, and what share that is. Of these papers, 129 (12%) mention no other test.

The 12 tests these papers mention most

708 papers 64%
454 papers 41%
398 papers 36%
189 papers 17%
78 papers 7%
32 papers 3%
22 papers 2%
21 papers 2%
18 papers 2%

Which papers count

A paper counts here when it is animal research, mentions the sucrose preference test in its title or abstract, and studies depression.

We tell whether a paper studies depression from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on depression research names the subject headings we count as depression. Download the test list for the search terms we used for the sucrose preference test, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on the sucrose preference test counts all the papers that mention it, whatever they study. The page on depression research ranks the tests by their papers on depression.

How to cite

APA

ConductScience. (2026, November 10). Sucrose preference test in depression research [Data set]. https://conductscience.com/data/behavioral-tests/models/depression/sucrose-preference-test

BibTeX

@misc{conductscience_depression_sucrose_preference_test_2026,
  author = {{ConductScience}},
  title = {Sucrose preference test in depression research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/depression/sucrose-preference-test},
  note = {Data set, released November 10, 2026},
}

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