ConductScience Cell Strainers 100um, Sterile (Bulk 10-Pack)
$52.00 per unit | 10 units per pack Bulk pricing: Bulk 10-Pack at $520.00 ($52.00 per unit)
| Automation Level | manual |
The ConductScience Cell Strainers 100um are sterile, single-use filtration devices designed for coarse tissue filtration in cell culture applications. These strainers feature a 100-micrometer nylon mesh that effectively separates larger tissue fragments, debris, and cell aggregates from single-cell suspensions while maintaining cell viability and sterility.
The 100um pore size provides optimal filtration for primary tissue dissociation protocols, removing fibrous tissue, undissociated cell clumps, and other particulates that could interfere with downstream applications such as cell counting, flow cytometry, or culture establishment. The sterile packaging ensures immediate use in aseptic cell culture workflows without additional sterilization steps.
How It Works
Cell strainers operate on the principle of size-exclusion filtration, where a precisely manufactured nylon mesh creates uniform pore openings that allow particles smaller than the pore diameter to pass through while retaining larger materials. The 100-micrometer pore size is specifically selected to retain tissue fragments, cell aggregates, and debris while permitting individual cells and small cellular components to pass through.
The nylon mesh material provides chemical inertness and minimal protein binding, ensuring that filtered cells maintain their native surface properties and viability. The mesh is supported by a rigid polystyrene frame that maintains structural integrity during filtration and prevents mesh deformation under pressure. The sterile manufacturing process eliminates endotoxins and viable microorganisms, making the strainers suitable for use in sterile cell culture environments.
Features & Benefits
Automation Level
- manual
Research Domain
- Cancer Research
- Cell Biology
- Developmental Biology
- Histopathology
- Immunology
- Neuroscience
Weight
- 30.92 kg
Dimensions
- L: 30.0 mm
- W: 25.0 mm
- H: 20.0 mm
Comparison Guide
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Pore Size | 100 micrometers for coarse tissue filtration | Entry-level products may offer limited pore size options | Optimized pore size removes large debris while maximizing single-cell recovery from tissue dissociations. |
| Sterility Assurance | Individually packaged sterile units | Some alternatives require user sterilization | Ready-to-use sterile packaging eliminates additional sterilization steps and reduces contamination risk. |
| Mesh Material | Nylon mesh construction | Various materials including metal or polymer meshes | Nylon provides chemical inertness and minimal protein binding for consistent cell recovery. |
| Single-Use Design | Disposable for single-use applications | Some alternatives are reusable but require cleaning validation | Eliminates cross-contamination concerns and cleaning validation requirements between samples. |
These strainers offer sterile, single-use convenience with nylon mesh construction optimized for coarse tissue filtration applications. The 100um pore size provides effective debris removal while maintaining high cell recovery rates in primary tissue processing workflows.
Practical Tips
Pre-wet the mesh with buffer or medium before sample application to improve flow characteristics and cell recovery.
Why: Pre-wetting reduces surface tension and prevents cell adhesion to dry mesh surfaces.
Pour samples slowly through the center of the strainer to prevent mesh damage and ensure uniform filtration.
Why: Controlled sample application prevents mesh deformation and ensures consistent pore accessibility.
Monitor filtration flow rate during processing to detect mesh clogging that may require sample dilution or alternative processing.
Why: Reduced flow rate indicates mesh saturation with debris that can compromise filtration efficiency.
Handle strainers only by the rim to maintain sterility and prevent mesh contact with non-sterile surfaces.
Why: Mesh contact with contaminated surfaces can introduce microorganisms into sterile cell preparations.
Rinse the mesh with small volumes of buffer to recover additional cells trapped in debris if maximum cell recovery is critical.
Why: Gentle rinsing can recover viable cells mechanically trapped in filtered debris without compromising sample purity.
If filtration becomes extremely slow, consider pre-filtering through a coarser strainer or diluting the sample with buffer.
Why: Heavy debris loading can block mesh pores and prevent efficient filtration of remaining sample volume.
Setup Guide
What’s in the Box
- 50 individually packaged sterile cell strainers (typical)
- Product documentation and specifications (typical)
Warranty
ConductScience provides standard warranty coverage for manufacturing defects, with technical support available for application guidance and troubleshooting.
Compliance
What is the effective pore size tolerance for these strainers?
Consult product datasheet for precise pore size specifications and tolerances. The 100um designation represents the nominal pore size for coarse filtration applications.
Can these strainers be used with enzymatic dissociation solutions?
The nylon mesh is chemically resistant to most enzymatic solutions used in tissue dissociation, but compatibility with specific enzyme formulations should be verified for extended contact applications.
What is the maximum filtration volume capacity?
Filtration capacity depends on sample type and debris content. Consult product datasheet for recommended maximum volumes and flow rate specifications.
How do these compare to finer mesh strainers for cell separation?
100um strainers are designed for coarse filtration and debris removal, while finer meshes (40um, 70um) provide more stringent cell separation and are typically used after initial coarse filtration.
Are these strainers compatible with automated cell processing systems?
The strainers are designed for manual use but may be compatible with certain automated systems depending on the system's strainer holder specifications.
What is the recommended storage condition for unused strainers?
Store in original sterile packaging at room temperature in a dry environment, protected from direct sunlight and extreme temperatures.
Can the strainers be pre-treated to improve cell recovery?
Pre-wetting with appropriate buffer or medium can improve flow characteristics and cell recovery, particularly for samples with high protein content.
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