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Rodent Tremor Monitor

See more by: MazeEngineers

$5,900.00$6,900.00

10% off with your subscription Membership
 / Availability: In Stock / Delivery Info ⓘ

Description

The rodent tremor monitor system from Maze Engineers serves to assess tremors in rodents, which are involuntary, rhythmic muscle contractions triggered by various factors. These include neurological conditions like stroke, multiple sclerosis, traumatic brain injury, or Parkinson’s disease; pharmacological issues such as mercury poisoning; and metabolic disturbances like hypoglycemia. This system is instrumental in diagnosing tremors definitively and monitoring their real-time response to treatment. It offers multiple chamber configurations with customizable specifications and dimensions.

Key parameters measurable with the rodent tremor monitor system include the type of tremor, its severity, and how it responds to treatment.

Here are some of the benefits of using a rodent tremor monitor system:

  • Accurate tremor measurement: The rodent tremor monitor system is a very accurate way to measure tremors. The system can detect tremors that are too subtle to be seen with the naked eye.
  • Quantitative tremor analysis: The rodent tremor monitor system can be used to quantitatively analyze tremors. This means that the system can be used to measure the severity of the tremor, the frequency of the tremor, and the amplitude of the tremor.
  • Tremor monitoring over time: The rodent tremor monitor system can be used to monitor tremors over time. This means that the system can be used to track the progression of tremors and assess the response of tremors to treatment.

Meet the producer

Producer: MazeEngineers

MazeEngineers offers custom-built behavioral mazes at no extra cost—designed to fit your exact research needs. Eliminate reproducibility issues from poor sizing or lingering scent cues with precision-engineered, modular, and smart mazes that adapt in real time to animal behavior. Publish new protocols, run adaptive experiments, and push the boundaries of behavioral science.

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Frequently bought together

Description

Mouse Features

Sound attenuating chamber

Mouse Enclosure

Tremor Sensor

Conduct software

Rat Features

Sound attenuating chamber

Mouse Enclosure

Tremor Sensor

Conduct software

Take advantage of Neuralynx, Ethovision Integration, SMS and Email integration with the Conductor Science Software. No I/O Boxes Required

Features

Sound Attenuating Cubicle
  • 55cm x 42cm x 55cm (width x depth x height) (dimensions are customizable, please request)
  • Multi-layer sound-proof insulation material that attenuates environmental disturbance
  • LED house light (manual)
  • Automated IR light
  • Automated air circulation fan
  • Camera mount
  • Pull-out floor shelf (optional)
Rodent Enclosure
  • Acrylic cage with lid
  • Dimensions: mouse 17 x 17 x 25cm (width x depth x height) cm and rat 26 x 26 x 30 cm (width x depth x height)
  • Front circular door – The door open in the middle
  • Feces and urine tray – removable for feces and urine removal
Control Box
  • Support up to eight Tremor Monitor stations: Each station has one control box that controls its operations
  • The main control box connects to up to 16 chamber control boxes via wireless communication. The wireless
    eliminates many cable connections between the main control box and all (up to 8) stations
  • The main controller connects to the PC via a USB (RS-232) cable and communicates with Maze Engineers
    Conduct Tremor software on the PC
Conduct Software
  • No TTL is required
  • Export real-time recorded data from the control box to PC
  • The Conduct Tremor software is used to configure and run experiments. The software is intuitive and precise
    with easy installation
  • The user can specify frequencies (for example at 128Hz) to be monitored
  • The data are presented and charted for analysis via FFT that shows the most powerful frequency recorded
  • The ability to run up to 60 minutes and the data can be reviewed in adjustable intervals such as 1-minute or 2-
    minutes
  • Support up to 8 stations simultaneously
Tremor sensor
  • Ultra-sensitive piezoelectric disk
  • Record continuous movement waveforms at 1 to 128 (Hz) in real-time for up to 60 minutes

Apparatus and Equipment

The design of the Rodent Tremor Chamber integrates a sound-attenuating enclosure, rodent support apparatus, tremor detection sensor, and software suite for recording, analyzing, and exporting data.

Rodents modeled for tremors and control strains are securely positioned within the holder to facilitate precise tremor analysis.

For accurate rodent positioning, advanced video tracking software solutions like Noldus EthoVision, ANY-Maze, or BehaviorCloud can be utilized to monitor rodent movements within the chamber.

Training Protocol

Set up protocol parameters using the Conduct software package, including experimental timing and other variables.
Introduce subjects into the rodent enclosure and provide a 10-minute habituation period.
Initiate tremor measurement using the Conduct software.
Record tremor frequencies and event counts, exporting the data to a PC for further analysis.

Data Analysis

The following parameters can be measured using te rodent temor chamber:

  • Number of tremors in a given time
  • Type of tremor
  • The severity of the tremor
  • Response of the tremor to treatment.

Literature Review

Summary

The Rodent Tremor Chamber allows for ultra-sensitive measurements of tremor in rat and mouse models.

  • The apparatus is composed of a sound-attenuating chamber, rodent enclosure, tremor sensor, control box, and Conduct software.
  •  Continuous movement waveforms can be recorded at 1-128 Hz in real-time for up to 60 minutes.

References

Gardner, D. R., Welch, K. D., Lee, S. T., Cook, D., & Riet-Correa, F. (2018). Tremorgenic Indole Diterpenes from Ipomoea asarifolia and Ipomoea muelleri and the Identification of 6,7-Dehydro-11-hydroxy-12,13-epoxyterpendole A. Journal of Natural Products, 81(7), 1682–1686. doi:10.1021/acs.jnatprod.8b00257

Paterson, N. E., Malekiani, S. A., Foreman, M. M., Olivier, B., & Hanania, T. (2009). Pharmacological characterization of harmaline-induced tremor activity in mice. European Journal of Pharmacology, 616(1-3), 73–80. doi:10.1016/j.ejphar.2009.05.031

Additional information

Species

Mouse, Rat

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