Multi-function Animal Anesthesia Solutions
The experimental system is equipped with a gas recovery system to provide a safe experimental environment to maximize the protection of the operator; by replacing different types of anesthesia machines and masks to meet the needs of animal experiments, such as cerebral ischemia and myocardial ischem
Louise Corscadden, PhD
Director of Science · ConductScience
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The system aims to provide one complete solution to both initial and lasting anesthesia of small rodents for the majority of procedures such as the development of animal disease models.
Specifications
Comes with the following items:
| SKU | Product Description | QTY |
|---|---|---|
| RWD-R510-29 | Gas Supply: Anesthesia Air Pump 110V (4L Flowmeter) | 1 |
| RWD-R550IP | Anesthesia Machine | 1 |
| RWD-V100 | Induction Chamber - Mouse or Rat | 1 |
| RWD-68680 | Cone mask with tubing for 1 animal (Your choice) | 5 |
| RWD-R510-31-6 | Gas Canister Filter | 6 |
| RWD-68657 | Manifold for 5 Cone Masks | 1 |
| RWD-R510-31S-6 | Gas Canister Filter, Small | 1 |
Manufacturer Source: https://www.rwdstco.com/product-item/multi-function-anesthesia-solutions/
How It Works
The system operates on the principle of controlled vaporization and delivery of volatile anesthetic agents, typically isoflurane or sevoflurane. The anesthesia machine precisely controls the concentration of anesthetic vapor mixed with carrier gas (air) through a calibrated vaporizer system. The 4L flowmeter air pump provides consistent carrier gas flow, while the precision anesthesia machine regulates anesthetic concentration and flow rate distribution.
During induction, animals are placed in the enclosed induction chamber where higher anesthetic concentrations (typically 3-5%) rapidly achieve anesthetic depth. Once induced, animals are transferred to individual cone masks connected to the manifold system for maintenance anesthesia at lower concentrations (1.5-2.5%). The manifold design allows simultaneous anesthesia delivery to multiple animals while maintaining individual flow control.
Gas filtration components remove moisture and contaminants from the anesthetic stream, ensuring consistent delivery and protecting equipment integrity. The cone mask design provides secure fit while minimizing dead space, allowing rapid adjustment of anesthetic depth through concentration and flow rate modifications.
Features & Benefits
Automation Level
- semi-automated
Device Type
- Single Cone Mask
Brand
- RWD
Research Domain
- Addiction Research
- Aging Research
- Anxiety and Depression
- Behavioral Pharmacology
- Cancer Research
- Cardiovascular
- Histopathology
- Learning and Memory
- Metabolic Research
- Motor Function
- Neurodegeneration
- Neuroscience
- Pain Research
- Toxicology
Species
- Mouse
- Rat
Weight
- 8.27 kg
Dimensions
- L: 34.0 mm
- W: 39.0 mm
- H: 33.0 mm
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Multi-animal capacity | 5-animal manifold system with individual cone masks | Single animal systems or basic multi-port distributors without precision control | Enables simultaneous procedures across multiple subjects while maintaining individual anesthetic delivery control. |
| Air supply system | Integrated 4L flowmeter air pump (110V) eliminating external gas requirements | Systems requiring external compressed gas tanks or medical air connections | Reduces setup complexity and eliminates ongoing costs for compressed gas supplies. |
| Induction capability | Dedicated RWD-V100 induction chamber for mice or rats | Basic chambers or cone-mask-only induction methods | Provides controlled induction environment reducing stress and improving anesthesia consistency. |
| Filtration system | Multi-level gas filtration with 6 standard plus 1 small canister filter | Minimal filtration or single-stage systems | Ensures consistent anesthetic delivery and protects equipment from contamination for reliable long-term operation. |
| System integration | Complete turnkey system with precision anesthesia machine, pump, chamber, and manifold | Component-based systems requiring separate sourcing and integration | Eliminates compatibility concerns and reduces setup time with pre-configured component matching. |
| Equipment classification | Single cone mask device type for individual animal precision control | Basic distribution systems without precision flow management | Enables precise anesthetic delivery protocols required for reproducible research outcomes. |
This system provides comprehensive multi-animal anesthesia capabilities with integrated air supply and precision control components. The complete package approach eliminates component compatibility issues while the integrated air pump reduces facility requirements compared to compressed gas dependent systems.
Practical Tips
Verify anesthetic concentration output using calibrated gas analyzer before beginning experimental protocols.
Why: Ensures accurate anesthetic delivery concentrations match protocol requirements for reproducible results.
Establish regular filter replacement schedules based on usage volume rather than time intervals alone.
Why: Filter saturation depends on usage intensity and prevents flow restriction that could affect anesthetic delivery.
Allow animals to recover in warm environment with supplemental oxygen when transitioning from anesthesia.
Why: Supports normal thermoregulation and respiratory function during the vulnerable recovery period.
Monitor respiratory rate and depth continuously during anesthesia delivery, especially during induction phase.
Why: Provides early indication of appropriate anesthetic depth and prevents over-anesthetization.
Check all connections for leaks if experiencing inconsistent anesthetic delivery or unexpected animal awakening.
Why: Gas leaks reduce delivered concentration and compromise anesthetic maintenance.
Record anesthetic concentrations, flow rates, and timing for each experimental session in laboratory protocols.
Why: Documentation enables protocol reproducibility and helps identify variables affecting experimental outcomes.
Implement waste anesthetic gas scavenging to minimize personnel exposure in confined laboratory spaces.
Why: Reduces occupational exposure to volatile anesthetics protecting laboratory staff health and safety.
Setup Guide
What’s in the Box
- RWD-R510-29 Gas Supply: Anesthesia Air Pump 110V (4L Flowmeter) - 1 unit
- RWD-R550IP Anesthesia Machine - 1 unit
- RWD-V100 Induction Chamber - Mouse or Rat - 1 unit
- RWD-68680 Cone mask with tubing for 1 animal - 5 units
- RWD-R510-31-6 Gas Canister Filter - 6 units
- RWD-68657 Manifold for 5 Cone Masks - 1 unit
- RWD-R510-31S-6 Gas Canister Filter, Small - 1 unit
- Power cord and connection hardware (typical)
- User manual and setup documentation (typical)
Warranty
ConductScience provides a one-year manufacturer warranty covering defects in materials and workmanship, with technical support for setup and operational guidance.
Compliance
References
Background reading relevant to this product:
What anesthetic agents are compatible with this system?
The system is designed for use with standard volatile anesthetics including isoflurane and sevoflurane. Consult the anesthesia machine specifications for specific agent compatibility and vaporizer requirements.
Can the system deliver different anesthetic concentrations to each animal simultaneously?
The manifold system distributes a common anesthetic concentration to all outlets. Individual concentration control requires separate anesthesia machines or sequential use of the single machine with different settings.
What flow rates does the 4L flowmeter air pump provide?
Consult the RWD-R510-29 specifications for exact flow rate ranges. Typical small animal anesthesia systems provide 0.5-4 L/min flow rates adjustable for different body weights and procedural requirements.
How frequently should the gas canister filters be replaced?
Filter replacement frequency depends on usage intensity and environmental conditions. Monitor filter indicators if present, or establish replacement schedules based on flow volume and visible contamination per manufacturer guidelines.
Is the induction chamber suitable for both mice and rats?
Yes, the RWD-V100 induction chamber is specified for both mice and rats. Chamber volume and design accommodate the size range of these species for effective induction procedures.
What maintenance procedures are required for consistent operation?
Regular maintenance includes filter replacement, cleaning of cone masks and tubing, calibration verification of the anesthesia machine, and inspection of all connections for leaks or wear.
Can the system operate without external compressed gas?
Yes, the included 4L flowmeter air pump (RWD-R510-29) provides carrier gas from room air, eliminating the need for compressed oxygen or medical air sources.
What safety features protect against anesthetic overdose?
Safety depends on proper training and protocol adherence. The precision anesthesia machine provides concentration control, but operators must monitor animals continuously and maintain appropriate anesthetic depth through proper technique.
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