Stereotaxic Multi-function Spinal Cord Adaptor for Rat and Mouse
Stereotaxic Spinal Cord Adaptor (for SCI experiments) SCI: Spinal Cord Injury with the Precise Impactor Device.
| support_method | Supporting the spinal cord from the lower sides of the spine |
| platform_type | Three-axis micro-manipulated rotatable platform |
| adjustment_device | Universal adjustment device for spinal cord level adjustment |
| strike_orientation | Vertical strikes |
| depth_error_prevention | Avoids depth error caused by animal collapse during breathing or impact |
| Automation Level | manual |
This adaptor includes ear bars and raising block (65mm). It holds the head through ear canal and eye socket. The adaptor can be used with standard stereotaxic instruments and large animal stereotaxic instruments.
This adapter is used for large animal stereotaxic instrument, and it is ideal for dogs, monkeys and pigs around 10kg. The extended palate and screw is convenient to hold the animal firmly.
It holds the rabbit head by special malar clamp, adjustable incisor buckle and nose bar. The distance between the two zygomatic clamps can be precisely adjusted by the screw knob. Ward and backward adjustable range of adult rabbit is 43.5mm, neonatal rabbit is 26.5mm and the adaptor is 40mm.Up and down angle adjusting range: 135°（-67.5°~+67.5°）
: 9, 19-20/F, Building 7A, 9F Building 7D,
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How It Works
The adaptor operates on a three-axis micro-manipulated positioning principle that provides independent control over anteroposterior, mediolateral, and dorsoventral coordinates. The system supports the animal from the lower sides of the spine rather than through dorsal pressure, which maintains natural spinal curvature and reduces tissue deformation during procedures.
The universal adjustment mechanism allows precise positioning across different spinal cord levels while the rotatable platform accommodates varying surgical approaches. The design compensates for respiratory movement artifacts through stable lateral support, preventing the depth errors commonly encountered when animals experience breathing-induced positional shifts during procedures.
Vertical strike orientation ensures consistent needle trajectories perpendicular to the spinal cord surface, critical for accurate targeting of specific laminae or nuclei within the cord's complex three-dimensional structure.
Features & Benefits
support_method
- Supporting the spinal cord from the lower sides of the spine
platform_type
- Three-axis micro-manipulated rotatable platform
adjustment_device
- Universal adjustment device for spinal cord level adjustment
strike_orientation
- Vertical strikes
depth_error_prevention
- Avoids depth error caused by animal collapse during breathing or impact
Automation Level
- manual
Species
- Mouse
- Rat
Brand
- RWD
Research Domain
- Behavioral Pharmacology
- Developmental Biology
- Motor Function
- Neurodegeneration
- Neuroscience
- Pain Research
Weight
- 8.27 kg
Dimensions
- L: 34.0 mm
- W: 39.0 mm
- H: 33.0 mm
Comparison Guide
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Positioning Axes | Three-axis micro-manipulated rotatable platform | Many basic adaptors offer single-axis or fixed positioning | Independent control over all spatial dimensions enables precise targeting of specific spinal cord laminae and nuclei. |
| Spine Support Method | Lateral support from lower sides of spine | Conventional systems often use dorsal pressure or clamping | Maintains natural spinal curvature while preventing tissue compression artifacts that can affect experimental outcomes. |
| Adjustment Range | Universal adjustment device for multiple spinal levels | Fixed-position adaptors require repositioning for different segments | Accommodates procedures across cervical to lumbar segments within single setup, reducing preparation time. |
| Movement Compensation | Designed to prevent depth errors from respiratory movement | Basic systems may lack respiratory movement compensation | Reduces measurement variability and improves reproducibility in precise targeting applications. |
| Species Compatibility | Accommodates both mouse and rat anatomies | Species-specific adaptors often require separate units | Single adaptor serves multiple rodent models, reducing equipment costs and storage requirements. |
| Strike Orientation | Vertical strikes perpendicular to spinal cord surface | Varies by model and mounting configuration | Consistent perpendicular trajectories ensure reproducible depth measurements across experiments. |
This adaptor offers comprehensive three-axis positioning control with specialized lateral spine support that maintains anatomical integrity. The universal adjustment system and respiratory movement compensation provide enhanced precision for targeted spinal cord interventions in both mouse and rat models.
Practical Tips
Verify coordinate zero points using consistent anatomical landmarks before each experimental session.
Why: Accurate calibration ensures reproducible targeting across animals and experimental days.
Allow the positioning platform to settle for 30-60 seconds after making adjustments before beginning injections.
Why: Mechanical settling prevents micro-movements that could affect injection accuracy.
Clean all contact surfaces with appropriate solvents after each use to prevent biological material buildup.
Why: Regular cleaning maintains smooth mechanical operation and prevents positioning drift.
Monitor anesthesia depth continuously as the prone positioning may affect respiratory mechanics.
Why: Spinal positioning can alter breathing patterns requiring careful anesthetic management.
If experiencing positioning drift, check that all lateral support points are making consistent contact with the animal.
Why: Uneven support can cause gradual positional shifts during procedures.
Record all coordinate settings and adjustment parameters for each animal to enable precise replication.
Why: Detailed documentation improves experimental reproducibility and troubleshooting capabilities.
Warm the adaptor components to room temperature before use if stored in cold environments.
Why: Temperature equilibration prevents condensation and ensures stable mechanical properties.
Setup Guide
What’s in the Box
- Stereotaxic spinal cord adaptor with three-axis platform
- Universal spinal level adjustment device
- Lateral spine support components
- Mounting hardware for stereotaxic frames
- User manual with coordinate reference tables (typical)
- Calibration verification tools (typical)
Warranty
ConductScience provides a one-year manufacturer warranty covering defects in materials and workmanship, with technical support for setup and calibration procedures.
Compliance
References
Background reading relevant to this product:
What coordinate accuracy can be achieved with the three-axis positioning system?
Consult product datasheet for specific positioning resolution specifications. The micro-manipulated platform provides precise control across all three spatial dimensions.
How does the adaptor prevent respiratory movement artifacts during injections?
The lateral spine support system stabilizes the animal from the lower sides rather than applying dorsal pressure, reducing movement transmission during breathing cycles.
What spinal cord levels can be accessed with the universal adjustment device?
The universal adjustment mechanism accommodates positioning across different vertebral levels from cervical to lumbar segments within a single experimental setup.
Is the adaptor compatible with existing stereotaxic equipment?
Yes, the adaptor is designed for integration with standard stereotaxic instruments using conventional mounting hardware without frame modifications.
What injection volumes and rates are recommended for spinal cord procedures?
Typical protocols use 1 μL volumes delivered at 200 nL/min rates, though optimal parameters depend on the specific experimental application and target region.
How are coordinate systems calibrated for different animal sizes?
The adaptor accommodates both mouse and rat anatomies through adjustable support positioning, with coordinate calibration performed using anatomical landmarks specific to each species.
What maintenance is required for the positioning mechanisms?
Regular inspection of adjustment mechanisms and cleaning of contact surfaces maintains positioning accuracy. Lubrication schedules depend on usage frequency.
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