Conscious Mouse Stereotaxic Precision Locator
Conscious mouse stereotaxic precision locator for awake head-fixed brain research, with digital single-manipulator positioning and selectable disk, rolling ball, rolling wheel, and rolling drum behavioral platform configurations for two-photon imaging, electrophysiology, optogenetics, microdialysis, and related neural recording workflows.
Louise Corscadden, PhD
Director of Science · ConductScience
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Key Specifications
Full details →- Model fit
- 5 selectable configurations
- SKU family
- CS-SAMP-30-1351/CS-SAMP-30-1352/CS-SAMP-30-1353/CS-SAMP-30-1354/CS-SAMP-30-2091
- Shipping box
- 30.0 × 25.0 × 25.0 cm
- Ordering
- Online checkout and quote request available
- Category
- Restrainers
- Build notes
- Confirm accessories, station layout, and support needs before purchase
Overview
The Conscious Mouse Stereotaxic Precision Locator is an awake mouse stereotaxic positioning system for laboratories that need stable cranial access while the animal remains conscious in a controlled behavioral scene. The product family uses digital single-manipulator positioning and lets the lab select a disk, rolling ball, rolling wheel, or rolling drum platform configuration for head-fixed mouse brain research.
The buying value is the combination of skull fixation, precision targeting, and an awake platform choice on one existing ConductScience page. Instead of treating the locator as a generic frame, this listing is organized around the experiments scientists actually plan around it: two-photon imaging, patch clamp recording, optogenetics, endogenous optical imaging, cyclic voltammetry, ion sensing, microdialysis analysis, and multichannel silicon electrode recording.
Use this page when the workflow needs a conscious mouse stereotaxic precision locator rather than a standard anesthetized stereotaxic frame or a head-fixed treadmill. The locator supports brain-positioning and platform selection; the surrounding station should be completed with the microscope, recording or stimulation hardware, microdialysis or electrode path, head-fixing plates, warming, monitoring, and preparation-support equipment selected for the study.
Scientific Use
Awake head-fixed mouse workflows are used when anesthesia would interfere with the neural activity, behavioral state, sensory processing, or physiological context being measured. The selectable platform types give the lab a way to match the animal support surface to imaging, recording, optical stimulation, microdialysis, voltammetry, ion sensing, or electrode-recording setups that require stable skull positioning.
The digital single-manipulator path helps position the brain-access hardware while the platform keeps the animal in the appropriate conscious support context. That makes the product most useful for functional brain studies where the station has to coordinate cranial stability, behavioral context, microscope or probe access, and animal-support planning.
Buying Fit
Choose the disk platform for a compact stable scene, rolling ball or rolling wheel configurations when the study benefits from mouse movement context, and rolling drum when that platform geometry better fits the behavior, imaging, or recording setup. ConductScience can review the selected platform with head-fixing plates, stereotaxic holders, microscopy, electrophysiology, optogenetics, microdialysis, anesthesia transition, warming, and monitoring products before fulfillment.
How It Works
The system operates through precise skull fixation that maintains stereotaxic coordinates while permitting natural movement within defined behavioral paradigms. The positioning apparatus secures the animal's head using a custom mounting system that interfaces with chronically implanted head plates or stereotaxic anchors. This approach preserves neural circuit integrity while providing stable access for recording electrodes, optical fibers, or imaging systems.
Multiple platform configurations accommodate different experimental requirements: turntable systems enable rotational movement studies, rolling balls provide omnidirectional locomotion, rollers support linear movement paradigms, and rotary drums create controlled exercise environments. Each platform maintains consistent head positioning relative to recording equipment while the animal engages in species-appropriate behaviors.
The digital display system provides real-time feedback on positioning coordinates and movement parameters, ensuring experimental reproducibility. The single-arm design minimizes mechanical constraints while maintaining the precision required for targeted brain region access, enabling researchers to correlate specific neural activity with behavioral outputs in conscious animals.
Features & Benefits
Workflow fit
- Awake/conscious mouse head-fixed stereotaxic brain research
Positioning path
- Digital single-manipulator conscious mouse stereotaxic positioning
Behavioral scene
- Disk, rolling ball, rolling wheel, or rolling drum platform selection
Research applications
- Two-photon imaging, patch clamp, optogenetics, endogenous optical imaging, cyclic voltammetry, ion sensing, microdialysis, and multichannel silicon electrode recording
Plan with
- Headplates, microscope, recording or optogenetics hardware, microdialysis hardware, preparation support, warming, and monitoring
Current price
- $3,958.99 regular price
Shipping weight
- 17.64 lb
Shipping box
- L: 30.0 cm
- W: 25.0 cm
- H: 25.0 cm
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Animal State During Recording | Conscious/awake animals with natural behavioral expression | Most systems require anesthesia for stable recordings | Eliminates anesthesia-induced neural suppression and enables study of authentic brain activity patterns |
| Platform Configuration Options | Five models with turntable, rolling ball, roller, rotary drum, and 3-piece set options | Limited to single behavioral paradigms | Accommodates diverse experimental designs within a standardized positioning framework |
| Movement Freedom | Skull fixation with preserved body mobility for behavioral tasks | Complete immobilization or unconstrained movement | Balances recording stability requirements with natural behavior expression for physiologically relevant data |
| Recording Modality Compatibility | Supports optogenetics, electrophysiology, and microscopy simultaneously | Often limited to single recording techniques | Enables comprehensive neural circuit analysis through multimodal approaches in conscious animals |
| Digital Coordinate Display | Real-time positioning feedback with digital readout | Manual coordinate systems or basic displays | Improves experimental reproducibility and enables precise documentation of recording locations |
| Single-Arm Design | Minimized mechanical constraints with maintained stereotaxic precision | Multi-arm systems with greater mechanical bulk | Reduces interference with natural movement patterns while preserving targeting accuracy |
The SCM100D series provides unique capability for neural recordings in conscious mice through specialized skull fixation that preserves behavioral authenticity. The multiple platform configurations and digital coordinate system offer experimental flexibility and precision not available in traditional anesthetized preparations or completely unrestrained recording approaches.
| Model | SKU | Listed price | Status | Shipping box |
|---|---|---|---|---|
| Turntable | CS-SAMP-30-1351 | $3,958.99 | Available | 30.0 × 25.0 × 25.0 cm |
| Rolling Ball | CS-SAMP-30-1352 | $3,958.99 | Available | 30.0 × 25.0 × 25.0 cm |
| Roller | CS-SAMP-30-1353 | $3,958.99 | Available | 30.0 × 25.0 × 25.0 cm |
| Rotary Drum | CS-SAMP-30-1354 | $3,958.99 | Available | 30.0 × 25.0 × 25.0 cm |
| 3-Piece set | CS-SAMP-30-2091 | $3,958.99 | Available | 30.0 × 25.0 × 25.0 cm |
Practical Tips
Choose the disk, rolling ball, rolling wheel, or rolling drum configuration around the planned behavior scene and access hardware.
Why: The platform choice is the main configuration decision and should match the experiment geometry instead of being treated as a generic accessory.
Plan acclimation, head-fixing plate fit, and station geometry alongside the imaging, recording, stimulation, or microdialysis method.
Why: Awake head-fixed studies depend on both mechanical stability and a setup that the mouse can tolerate during the experimental workflow.
Review microscope clearance, manipulator access, cable or tubing paths, warming, monitoring, and any optogenetics, electrophysiology, or microdialysis accessories before ordering.
Why: The locator is only one part of a functional awake mouse neuroscience station; the surrounding hardware determines whether the setup is usable.
Setup Guide
What’s in the Box
- Selected digital conscious mouse stereotaxic precision locator configuration
- Digital single-manipulator positioning path for conscious mouse stereotaxic work
- Selected behavioral platform: disk, rolling ball, rolling wheel, or rolling drum
- Optional 3-piece platform accessory set reviewed when selected
- Custom head-fixing plates reviewed separately when the workflow requires them
- Microscope, recording, optogenetics, microdialysis, headplate, anesthesia transition, warming, and monitoring support reviewed around the selected workflow
Warranty
Support, replacement, and fulfillment terms are confirmed with the final quote and institutional purchasing requirements.
Compliance
Which platform configurations are available?
The selectable configurations are disk platform, rolling ball platform, rolling wheel platform, and rolling drum platform. The optional platform accessory set and custom head-fixing plates can be reviewed with the selected workflow.
What research workflows does this locator support?
It is designed for awake mouse brain-function workflows such as two-photon imaging, patch clamp recording, optogenetics, endogenous optical imaging, cyclic voltammetry, ion sensing, microdialysis analysis, and multichannel silicon electrode recording.
How is this different from the head-fixed treadmill system?
This locator is centered on conscious mouse stereotaxic positioning with selectable platform scenes. The head-fixed treadmill page is centered on belt locomotion and training during cranial access.
What should be reviewed with the locator?
Review head-fixing plates, microscope clearance, optical or electrophysiology hardware, microdialysis or probe paths, warming, monitoring, preparation anesthesia, and any ConductScience holder accessories needed to complete the station.
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