Research data · Disease model

Parkinson disease

From 2021 to 2025, 918 animal research papers on Parkinson disease mentioned at least one behavioral test, most often the rotarod.

That is 1.7 times the 555 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

918 animal research papers on Parkinson disease from 2021 to 2025 mentioned a test
1.7 times as many papers as in 2011 to 2015
36% of these papers mention the rotarod
62 of the 90 tests we track appear in these papers

The tests these papers mention

The pole test appears in 11% of the papers on Parkinson disease and in 0.5% of all 32,277 papers that mention a test. That makes it 22 times as common in this research. Each bar counts the papers from 2021 to 2025 on Parkinson disease that mention the test, with its share of the 918 papers. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

332 papers 36%
232 papers 25%
101 papers 11%
100 papers 11%
74 papers 8%
52 papers 6%
52 papers 6%
50 papers 5%
50 papers 5%
48 papers 5%
45 papers 5%
40 papers 4%
40 papers 4%
All 62 tests these papers mention
Papers on Parkinson disease from 2021 to 2025 that mention each test
TestPapersShare of the 918 papers on Parkinson diseaseShare of all 32,277 papers that mention a test
Rotarod33236%6%
Open field23225%12%
Pole test10111%under 1%
Catalepsy bar test10011%1%
Beam walking748%2%
Rotational behavior (rotometer)546%under 1%
Forced swim test526%9%
Gait analysis526%3%
Novel object recognition516%9%
Cylinder test505%1%
Morris water maze505%17%
Grip strength485%4%
Treadmill running455%6%
Elevated plus maze404%9%
Y-maze404%6%
Sucrose preference test334%5%
Wire hang and inverted grid303%1%
Negative geotaxis and climbing assays243%1%
Tail suspension test192%4%
Passive avoidance162%4%
Von Frey test121%4%
Light-dark box121%2%
T-maze101%1%
Fear conditioning81%6%
Wheel running81%3%
Hole-board81%1%
Skilled reaching71%under 1%
Operant conditioning71%3%
Object location test71%1%
Adhesive removal test61%under 1%
Nest building51%1%
Novel tank test51%1%
Barnes maze51%2%
Active avoidance (shuttle box)51%1%
Novelty-suppressed feeding51%1%
Grid walking (foot fault)4under 1%under 1%
Tail flick4under 1%2%
Olfactory tests4under 1%under 1%
Radial arm maze3under 1%1%
Self-grooming3under 1%1%
Formalin test3under 1%2%
Step-down avoidance3under 1%under 1%
Marble burying3under 1%1%
Splash test3under 1%under 1%
Hargreaves plantar test2under 1%1%
Self-administration2under 1%4%
Ladder rung walking2under 1%under 1%
Elevated zero maze2under 1%under 1%
Three-chamber sociability test2under 1%1%
Cold plate2under 1%under 1%
Prepulse inhibition and acoustic startle2under 1%2%
Attentional set shifting2under 1%under 1%
Conditioned place preference2under 1%3%
Five-choice serial reaction time task2under 1%under 1%
Writhing test1under 1%2%
Predator odor exposure1under 1%1%
Resident-intruder test1under 1%under 1%
Touchscreen operant tasks1under 1%under 1%
Three-choice serial reaction time task1under 1%under 1%
Thermal gradient and temperature preference1under 1%under 1%
Hot plate1under 1%2%
Real-time place preference1under 1%under 1%

Papers by year

Animal research papers on Parkinson disease that mention a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200139
200241
200335
200450
200562
200660
200770
200863
200962
201080
201171
2012125
2013112
2014111
2015136
2016122
2017160
2018168
2019192
2020149
2021181
2022183
2023161
2024181
2025212
2026 (part year)168

Papers on Parkinson disease fell from 181 in 2021 to 161 in 2023, then rose to 212 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's disease models from PubMed's indexing whenever PubMed has indexed the paper, so part of this dip may come from the indexing rather than from fewer studies.

Which species the papers used

Each bar is a share of the 918 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
492 papers 54%
Rat
409 papers 45%
Fruit fly
27 papers 3%
Other animals
15 papers 2%
Zebrafish
13 papers 1%

“Other animals” counts papers that use none of the other species in this chart.

Which papers count

A paper counts here when it is animal research, mentions at least one of the 90 tests and studies Parkinson disease.

A paper counts under Parkinson disease when its MeSH terms, the subject headings PubMed adds when it indexes a paper, include one of these.

  • Parkinson Disease
  • Parkinsonian Disorders
  • Parkinson Disease, Secondary
  • MPTP Poisoning

For a paper PubMed has not indexed, PubTator 3, NCBI's text-mining service, supplies the disease model when it finds the disease in the title or abstract. A paper can count under more than one disease model.

Each paper and its disease models are in the downloads. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More disease models

These disease models also have a page, with their papers from 2021 to 2025 that mention a test. Each disease model with 100 or more such papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Behavioral tests in Parkinson disease research [Data set]. https://conductscience.com/data/behavioral-tests/models/parkinsons-disease

BibTeX

@misc{conductscience_parkinsons_disease_2026,
  author = {{ConductScience}},
  title = {Behavioral tests in Parkinson disease research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/parkinsons-disease},
  note = {Data set, released November 10, 2026},
}

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