Research data · Disease model

Sleep loss and sleep disorders

From 2021 to 2025, 400 animal research papers on sleep loss and sleep disorders mentioned at least one behavioral test, most often the Morris water maze.

That is 2.4 times the 167 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

400 animal research papers on sleep loss and sleep disorders from 2021 to 2025 mentioned a test
2.4 times as many papers as in 2011 to 2015
28% of these papers mention the Morris water maze
55 of the 90 tests we track appear in these papers

The tests these papers mention

Each bar counts the papers from 2021 to 2025 on sleep loss and sleep disorders that mention the test, with its share of the 400 papers. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

111 papers 28%
93 papers 23%
61 papers 15%
52 papers 13%
35 papers 9%
27 papers 7%
19 papers 5%
19 papers 5%
14 papers 4%
10 papers 3%
10 papers 3%
All 55 tests these papers mention
Papers on sleep loss and sleep disorders from 2021 to 2025 that mention each test
TestPapersShare of the 400 papers on sleep loss and sleep disordersShare of all 32,277 papers that mention a test
Morris water maze11128%17%
Open field9323%12%
Elevated plus maze6115%9%
Forced swim test5213%9%
Novel object recognition4010%9%
Y-maze359%6%
Tail suspension test338%4%
Sucrose preference test297%5%
Fear conditioning277%6%
Rotarod195%6%
Passive avoidance195%4%
Treadmill running144%6%
Wheel running103%3%
Self-administration103%4%
Light-dark box103%2%
Prepulse inhibition and acoustic startle82%2%
Object location test82%1%
Grip strength72%4%
Three-chamber sociability test51%1%
Barnes maze51%2%
Conditioned place preference51%3%
Von Frey test51%4%
Hot plate41%2%
Social interaction test41%1%
Marble burying41%1%
Splash test41%under 1%
Beam walking41%2%
Predator odor exposure31%1%
Radial arm water maze31%under 1%
Formalin test31%2%
Hole-board31%1%
Hargreaves plantar test31%1%
Attentional set shifting21%under 1%
Radial arm maze21%1%
Novelty-suppressed feeding21%1%
T-maze21%1%
Step-down avoidance21%under 1%
Catalepsy bar test21%1%
Learned helplessness21%under 1%
Operant conditioning21%3%
Nest building21%1%
Tail flick21%2%
Self-grooming21%1%
Skilled reaching1under 1%under 1%
Active avoidance (shuttle box)1under 1%1%
Negative geotaxis and climbing assays1under 1%1%
Five-choice serial reaction time task1under 1%under 1%
Touchscreen operant tasks1under 1%under 1%
Novel tank test1under 1%1%
Drug discrimination1under 1%under 1%
Writhing test1under 1%2%
Adhesive removal test1under 1%under 1%
Gait analysis1under 1%3%
Pole test1under 1%under 1%
Elevated zero maze1under 1%under 1%

Papers by year

Animal research papers on sleep loss and sleep disorders that mention a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20013
20024
20036
200413
200511
200611
200714
200819
200924
201021
201131
201222
201335
201436
201543
201639
201746
201850
201950
202065
202160
202274
202363
202493
2025110
2026 (part year)110

Which species the papers used

Each bar is a share of the 400 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
229 papers 57%
Rat
171 papers 43%
Other animals
8 papers 2%
Zebrafish
3 papers 1%
Fruit fly
3 papers 1%

“Other animals” counts papers that use none of the other species in this chart.

Which papers count

A paper counts here when it is animal research, mentions at least one of the 90 tests and studies sleep loss and sleep disorders.

A paper counts under sleep loss and sleep disorders when its MeSH terms, the subject headings PubMed adds when it indexes a paper, include one of these.

  • Sleep Deprivation
  • Sleep Wake Disorders, with the headings under it
  • Sleep Initiation and Maintenance Disorders

For a paper PubMed has not indexed, PubTator 3, NCBI's text-mining service, supplies the disease model when it finds the disease in the title or abstract. A paper can count under more than one disease model.

Each paper and its disease models are in the downloads. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More disease models

These disease models also have a page, with their papers from 2021 to 2025 that mention a test. Each disease model with 100 or more such papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Behavioral tests in sleep loss and sleep disorders research [Data set]. https://conductscience.com/data/behavioral-tests/models/sleep

BibTeX

@misc{conductscience_sleep_2026,
  author = {{ConductScience}},
  title = {Behavioral tests in sleep loss and sleep disorders research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/sleep},
  note = {Data set, released November 10, 2026},
}

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