Research data · Disease model

Obesity and high-fat diet

From 2021 to 2025, 761 animal research papers on obesity and high-fat diet mentioned at least one behavioral test, most often treadmill running.

That is 2.1 times the 370 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

761 animal research papers on obesity and high-fat diet from 2021 to 2025 mentioned a test
2.1 times as many papers as in 2011 to 2015
21% of these papers mention treadmill running
59 of the 90 tests we track appear in these papers

The tests these papers mention

Wheel running appears in 12% of the papers on obesity and high-fat diet and in 3.1% of all 32,277 papers that mention a test. That makes it 4.0 times as common in this research. Each bar counts the papers from 2021 to 2025 on obesity and high-fat diet that mention the test, with its share of the 761 papers. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

160 papers 21%
122 papers 16%
93 papers 12%
75 papers 10%
75 papers 10%
71 papers 9%
56 papers 7%
40 papers 5%
19 papers 2%
17 papers 2%
17 papers 2%
All 59 tests these papers mention
Papers on obesity and high-fat diet from 2021 to 2025 that mention each test
TestPapersShare of the 761 papers on obesity and high-fat dietShare of all 32,277 papers that mention a test
Treadmill running16021%6%
Morris water maze12216%17%
Wheel running9312%3%
Novel object recognition9012%9%
Elevated plus maze7510%9%
Open field7510%12%
Grip strength719%4%
Y-maze567%6%
Forced swim test405%9%
Sucrose preference test365%5%
Passive avoidance192%4%
Tail suspension test192%4%
Object location test182%1%
Rotarod172%6%
Fear conditioning172%6%
Operant conditioning132%3%
T-maze132%1%
Von Frey test132%4%
Self-administration122%4%
Barnes maze111%2%
Light-dark box111%2%
Marble burying101%1%
Negative geotaxis and climbing assays91%1%
Nest building81%1%
Social interaction test81%1%
Conditioned place preference71%3%
Elevated zero maze61%under 1%
Radial arm maze51%1%
Self-grooming41%1%
Novel tank test41%1%
Three-chamber sociability test41%1%
Gait analysis41%3%
Resident-intruder test3under 1%under 1%
Splash test3under 1%under 1%
Novelty-suppressed feeding3under 1%1%
Wire hang and inverted grid3under 1%1%
Hargreaves plantar test3under 1%1%
Step-down avoidance2under 1%under 1%
Prepulse inhibition and acoustic startle2under 1%2%
Olfactory tests2under 1%under 1%
Active avoidance (shuttle box)2under 1%1%
Writhing test1under 1%2%
Touchscreen operant tasks1under 1%under 1%
Radial arm water maze1under 1%under 1%
Formalin test1under 1%2%
Hebb-Williams maze1under 1%under 1%
Elevated T-maze1under 1%under 1%
Hot plate1under 1%2%
Predator odor exposure1under 1%1%
Hole-board1under 1%1%
Pole test1under 1%under 1%
Beam walking1under 1%2%
Five-choice serial reaction time task1under 1%under 1%
Real-time place preference1under 1%under 1%
Tube test for social dominance1under 1%under 1%
Thermal gradient and temperature preference1under 1%under 1%
Grid walking (foot fault)1under 1%under 1%
Corner test1under 1%under 1%
Acetone test1under 1%under 1%

Papers by year

Animal research papers on obesity and high-fat diet that mention a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20013
20025
20038
20048
20059
200610
200710
200824
200920
201036
201142
201262
201374
201476
2015116
2016113
2017135
2018129
2019142
2020146
2021134
2022152
2023140
2024153
2025182
2026 (part year)165

Which species the papers used

Each bar is a share of the 761 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
475 papers 62%
Rat
273 papers 36%
Other animals
11 papers 1%
Fruit fly
8 papers 1%
Zebrafish
5 papers 1%

“Other animals” counts papers that use none of the other species in this chart.

Which papers count

A paper counts here when it is animal research, mentions at least one of the 90 tests and studies obesity and high-fat diet.

A paper counts under obesity and high-fat diet when its MeSH terms, the subject headings PubMed adds when it indexes a paper, include one of these.

  • Obesity, with the headings under it
  • Pediatric Obesity
  • Diet, High-Fat

For a paper PubMed has not indexed, PubTator 3, NCBI's text-mining service, supplies the disease model when it finds the disease in the title or abstract. A paper can count under more than one disease model.

Each paper and its disease models are in the downloads. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More disease models

These disease models also have a page, with their papers from 2021 to 2025 that mention a test. Each disease model with 100 or more such papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Behavioral tests in obesity and high-fat diet research [Data set]. https://conductscience.com/data/behavioral-tests/models/obesity

BibTeX

@misc{conductscience_obesity_2026,
  author = {{ConductScience}},
  title = {Behavioral tests in obesity and high-fat diet research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/obesity},
  note = {Data set, released November 10, 2026},
}

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