Research data · Disease model

Psychological stress

From 2021 to 2025, 1,484 animal research papers on psychological stress mentioned at least one behavioral test, most often the forced swim test.

That is 10% fewer than the 1,646 papers of 2011 to 2015. Papers that mention any of the 90 tests rose 22% over the same span. The 2021 to 2025 count may run low because of a dip in PubMed's indexing, explained under the year chart.

1,484 animal research papers on psychological stress from 2021 to 2025 mentioned a test
10% fewer papers than in 2011 to 2015
42% of these papers mention the forced swim test
63 of the 90 tests we track appear in these papers

The tests these papers mention

The sucrose preference test appears in 32% of the papers on psychological stress and in 4.7% of all 32,277 papers that mention a test. That makes it 6.8 times as common in this research. Each bar counts the papers from 2021 to 2025 on psychological stress that mention the test, with its share of the 1,484 papers. A paper that mentions two tests counts under both.

The 15 tests these papers mention most

627 papers 42%
384 papers 26%
324 papers 22%
292 papers 20%
100 papers 7%
93 papers 6%
58 papers 4%
40 papers 3%
39 papers 3%
All 63 tests these papers mention
Papers on psychological stress from 2021 to 2025 that mention each test
TestPapersShare of the 1,484 papers on psychological stressShare of all 32,277 papers that mention a test
Forced swim test62742%9%
Sucrose preference test47732%5%
Open field38426%12%
Elevated plus maze32422%9%
Tail suspension test29220%4%
Fear conditioning1007%6%
Morris water maze936%17%
Novel object recognition775%9%
Social interaction test755%1%
Novelty-suppressed feeding644%1%
Light-dark box584%2%
Predator odor exposure403%1%
Passive avoidance403%4%
Y-maze393%6%
Self-administration362%4%
Conditioned place preference342%3%
Prepulse inhibition and acoustic startle342%2%
Social approach and avoidance302%under 1%
Splash test302%under 1%
Wheel running282%3%
Treadmill running232%6%
Three-chamber sociability test211%1%
Learned helplessness211%under 1%
Resident-intruder test201%under 1%
Operant conditioning201%3%
Marble burying191%1%
Hole-board141%1%
Von Frey test141%4%
Elevated zero maze141%under 1%
Self-grooming141%1%
Barnes maze131%2%
Tail flick121%2%
Object location test111%1%
Hot plate111%2%
Nest building101%1%
Novel tank test91%1%
Active avoidance (shuttle box)81%1%
Rotarod6under 1%6%
T-maze6under 1%1%
Attentional set shifting5under 1%under 1%
Grip strength4under 1%4%
Tube test for social dominance4under 1%under 1%
Elevated T-maze4under 1%under 1%
Negative geotaxis and climbing assays3under 1%1%
Social operant tasks3under 1%under 1%
Looming stimulus3under 1%under 1%
Cincinnati water maze2under 1%under 1%
Five-choice serial reaction time task2under 1%under 1%
Skilled reaching1under 1%under 1%
Grid walking (foot fault)1under 1%under 1%
Writhing test1under 1%2%
Formalin test1under 1%2%
Step-down avoidance1under 1%under 1%
Adhesive removal test1under 1%under 1%
Radial arm maze1under 1%1%
Touchscreen operant tasks1under 1%under 1%
Vogel conflict test1under 1%under 1%
Cold plate1under 1%under 1%
Hargreaves plantar test1under 1%1%
Ladder rung walking1under 1%under 1%
Gait analysis1under 1%3%
Catalepsy bar test1under 1%1%
Beam walking1under 1%2%

Papers by year

Animal research papers on psychological stress that mention a behavioral test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200166
200274
200373
200492
2005141
2006170
2007185
2008258
2009257
2010261
2011274
2012289
2013303
2014378
2015402
2016364
2017382
2018404
2019391
2020349
2021343
2022210
2023183
2024319
2025429
2026 (part year)401

Papers on psychological stress fell from 343 in 2021 to 183 in 2023, then rose to 429 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's disease models from PubMed's indexing whenever PubMed has indexed the paper, so part of this dip may come from the indexing rather than from fewer studies.

Which species the papers used

Each bar is a share of the 1,484 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
779 papers 52%
Rat
679 papers 46%
Other animals
42 papers 3%
Zebrafish
16 papers 1%
Nonhuman primate
3 papers under 1%
Fruit fly
2 papers under 1%

“Other animals” counts papers that use none of the other species in this chart.

Which papers count

A paper counts here when it is animal research, mentions at least one of the 90 tests and studies psychological stress.

A paper counts under psychological stress when its MeSH terms, the subject headings PubMed adds when it indexes a paper, include this heading.

  • Stress, Psychological

For a paper PubMed has not indexed, PubTator 3, NCBI's text-mining service, supplies the disease model when it finds the disease in the title or abstract. A paper can count under more than one disease model.

Each paper and its disease models are in the downloads. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More disease models

These disease models also have a page, with their papers from 2021 to 2025 that mention a test. Each disease model with 100 or more such papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Behavioral tests in psychological stress research [Data set]. https://conductscience.com/data/behavioral-tests/models/stress

BibTeX

@misc{conductscience_stress_2026,
  author = {{ConductScience}},
  title = {Behavioral tests in psychological stress research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/stress},
  note = {Data set, released November 10, 2026},
}

Shop apparatus by test

Our store sells apparatus for nine of the 10 tests these papers mention most, all but novelty-suppressed feeding.

Shop all behavioral apparatus