
Rat and Mouse Stereotaxic Alignment System
Rat and mouse stereotaxic alignment system for fine three-dimensional skull leveling before coordinate-guided brain experiments, with sagittal tilt, coronal tilt, anterior/posterior, and midline alignment adjustment, fixed-height ear-bar and nose-clip positioning, optional nose-clip anesthesia path, non-metallic body tray support, and selectable single/dual manipulator plus manual 0.1 mm or digital 0.01 mm configurations.

Louise Corscadden, PhD
Neuroscience · ConductScience
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Overview
The Rat and Mouse Stereotaxic Alignment System is a rodent stereotaxic system for labs that need fine skull leveling before coordinate-guided brain work. The source design fixes the animal with ear bars and nose clip, then uses a multi-dimensional adjustment mechanism to fine-level the head and animal body through sagittal tilt, coronal tilt, anterior/posterior adjustment, and midline alignment.
The buying value is alignment efficiency and reproducibility. Instead of repeatedly lifting and resetting the ear bars or nose clip to correct head angle, the operator can use knob-based fine tuning after fixation, with self-locking alignment support called out in the source. That makes this page a strong fit for teams where skull leveling, midline centering, and consistent setup geometry are recurring issues in rodent stereotaxic workflows.
Four configurations are available from one page: single manipulator manual 0.1 mm, dual manipulator manual 0.1 mm, single manipulator digital 0.01 mm, and dual manipulator digital 0.01 mm. The source family also calls out a dual-use nose-clip post that switches between rat and mouse nose clips by 180 degree rotation, optional nose clip with anesthesia mask, non-metallic trays for insulation-blanket support, wide field-of-view access in front of the head, and compatibility planning for a rat/mouse spinal cord clip.
Scientific Use
Stereotaxic alignment is especially important when a study depends on reproducible skull-referenced coordinates for injections, cannula placement, electrode or probe placement, viral-vector delivery, lesion work, imaging-adjacent preparation, or repeated operator setup. The page is written for scientists comparing a standard frame, an open-base frame, a staged multi-arm mouse frame, and a head-leveling alignment system.
Choose this system when the purchasing decision centers on leveling the animal after fixation, minimizing repeated head manipulation, preserving a wide working field, and selecting the right manipulator/readout configuration. Complete the station with stereotaxic-compatible anesthesia, nose cone masks, warming, microdrill or syringe holders, atlas planning, and any spinal clip or adaptor workflow that needs to be reviewed with the frame.
Buying Fit
This is the best fit when a lab wants rat and mouse stereotaxic positioning plus a dedicated alignment mechanism for head leveling. Choose the Open-Base Rat and Mouse Stereotaxic Instrument when the main concern is open operating geometry, and choose the Multi-Arm Mouse Stereotaxic Instrument when the main concern is staging positioning, drill, and injection tools on a mouse workflow.
Features & Benefits
Configuration
- Single manipulator, manual 0.1 mm
- Dual manipulator, manual 0.1 mm
- Single manipulator, digital 0.01 mm
- Dual manipulator, digital 0.01 mm
Model fit
- Mouse and rat stereotaxic head-leveling workflows
Alignment axes
- Sagittal tilt, coronal tilt, anterior/posterior adjustment, and midline alignment
Setup advantage
- Knob fine tuning after fixation reduces repeated ear-bar and nose-clip repositioning
Coordinate readout
- Manual 0.1 mm or digital 0.01 mm configurations
Animal support
- Dual-use rat/mouse nose-clip post, optional nose clip with anesthesia mask, and non-metallic body tray for insulation-blanket support
Plan with
- Stereotaxic anesthesia, nose cone masks, holders, microdrill, syringe pump, warming, monitoring, atlas planning, and spinal clip/adaptor review
Practical Tips
Decide whether the study needs sagittal, coronal, anterior/posterior, and midline fine leveling before choosing a standard frame or alignment-system configuration.
Why: The product value is the source-backed ability to fine-level the fixed head and body through a multi-dimensional adjustment mechanism.
Choose manual 0.1 mm for standard rodent alignment work or digital 0.01 mm when finer coordinate readout is part of the purchasing requirement; choose dual manipulator for bilateral or parallel-tool workflows.
Why: The source family includes both manual/digital and single/dual manipulator choices, so the configuration should match how the lab actually targets and stages tools.
Review nose cone masks, stereotaxic-compatible anesthesia, warming or insulation support, microdrill holder, syringe holder, atlas planning, and spinal clip/adaptor needs with the frame request.
Why: The alignment system is most useful when fixation, animal support, and tool-holder layout are planned as one station.
Setup Guide
What’s in the Box
- Rat and mouse stereotaxic alignment base and head-positioning assembly
- Multi-dimensional adjustment mechanism for sagittal, coronal, anterior/posterior, and midline alignment
- Fixed-height ear-bar and nose-clip positioning workflow with forward/backward nose-clip travel
- Dual-use nose-clip post for rat or mouse nose-clip switching by 180 degree rotation
- Non-metallic animal body tray for insulation-blanket support
- Selectable single- or dual-manipulator configuration
- Selectable manual 0.1 mm or digital 0.01 mm coordinate configuration
- Optional nose clip with anesthesia mask reviewed during configuration
- Optional spinal cord clip compatibility reviewed during configuration
Warranty
Support, replacement, and fulfillment terms are confirmed with the final quote and institutional purchasing requirements.
Compliance
What does the alignment system add to a rodent stereotaxic setup?
It adds a multi-dimensional leveling mechanism for adjusting the fixed head and animal body through sagittal tilt, coronal tilt, anterior/posterior positioning, and midline alignment before coordinate-guided work begins.
Which configurations are available?
Four selectable configurations are available: single manipulator manual 0.1 mm, dual manipulator manual 0.1 mm, single manipulator digital 0.01 mm, and dual manipulator digital 0.01 mm.
Does it support both rat and mouse workflows?
Yes. The source family is specified for rat and mouse workflows and includes a dual-use nose-clip post that switches between rat and mouse nose clips by rotating the post 180 degrees.
When should I choose digital readout?
Choose a digital 0.01 mm configuration when the lab wants finer coordinate display during targeting and alignment review. Manual 0.1 mm configurations are the lower-cost path for standard rodent stereotaxic alignment.
What should be planned with the alignment frame?
Common additions include stereotaxic anesthesia, nose cone masks, warming or insulation-blanket support, microdrill holder, syringe holder, atlas planning, monitoring, and any spinal cord clip or adaptor workflow that needs configuration review.
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Accessories
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