Stereotaxic Syringe Holder
: 9, 19-20/F, Building 7A, 9F Building 7D,.
| syringe_holding_range | 3 mm to 12 mm |
| needle_holding_range | 0.3 mm to 1.5 mm |
| Automation Level | manual |
| Brand | RWD |
| Species | Mouse, Rat |
Holder is applicable for microinjection, which holds syringe and needle simultaneusly, and the clamping if the syringe is more stable. The syringe holding range is 3 mm to 12 mm and needle's is 0.3mm to 1.5mm.
How It Works
The stereotaxic syringe holder operates through a dual-clamping mechanism that provides independent securing of both the syringe barrel and injection needle. The adjustable barrel clamp accommodates syringes ranging from 3-12 mm in diameter, while the separate needle clamp secures needles from 0.3-1.5 mm diameter. This dual-point stabilization prevents movement artifacts during injection that could compromise targeting accuracy.
The holder mounts to standard stereotaxic manipulator arms, allowing precise three-dimensional positioning according to stereotaxic coordinates. During injection, the rigid clamping system maintains consistent needle position relative to the skull landmarks, ensuring accurate delivery to the intended brain structure. The separate needle clamp also prevents needle deflection under injection pressure, particularly important for deep brain targets or high-viscosity solutions.
Features & Benefits
syringe_holding_range
- 3 mm to 12 mm
needle_holding_range
- 0.3 mm to 1.5 mm
Automation Level
- manual
Research Domain
- Anxiety and Depression
- Behavioral Pharmacology
- Learning and Memory
- Neurodegeneration
- Neuroscience
- Pain Research
Brand
- RWD
Species
- Mouse
- Rat
Weight
- 8.27 kg
Dimensions
- L: 34.0 mm
- W: 39.0 mm
- H: 33.0 mm
Comparison Guide
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Syringe Compatibility Range | 3-12 mm barrel diameter | Many holders accommodate narrower ranges or single syringe sizes | Single holder accommodates multiple syringe types without requiring different accessories. |
| Needle Stabilization | Independent 0.3-1.5 mm needle clamp | Basic models rely only on syringe clamping | Prevents needle deflection under injection pressure, improving targeting accuracy. |
| Clamping System | Dual-point clamping (syringe + needle) | Single-point syringe clamping only | Enhanced stability reduces movement artifacts during precise coordinate-based injections. |
| Mounting Compatibility | Standard manipulator mounting | Some holders require specific adapters | Direct integration with existing stereotaxic systems without additional hardware. |
This holder's dual-clamping system provides enhanced injection stability compared to basic syringe-only holders, while accommodating a broad range of syringe and needle sizes for versatile research applications.
Practical Tips
Verify needle patency by expressing a small drop before each injection to ensure no blockage occurred during positioning.
Why: Blocked needles can create pressure artifacts and compromise injection accuracy.
Clean clamp contact surfaces with ethanol after each use to prevent buildup of dried solutions or tissue debris.
Why: Contamination can affect clamping grip and introduce variables between procedures.
Check needle tip position relative to manipulator coordinates before each session using a test injection into dye solution.
Why: Ensures the clamping system maintains consistent needle positioning across experimental sessions.
Support the needle manually during initial positioning to prevent bending when engaging the needle clamp.
Why: Fine needles can deform under excessive clamping force, affecting injection trajectories.
If injection resistance increases suddenly, check for needle obstruction rather than increasing pressure, which could cause tissue damage.
Why: High injection pressures can cause tissue trauma or needle displacement from the target site.
Record injection parameters including pressure, flow rate, and total volume to ensure reproducible delivery across subjects.
Why: Consistent injection parameters are critical for interpreting dose-response relationships and experimental outcomes.
Setup Guide
What’s in the Box
- Stereotaxic syringe holder assembly (typical)
- Syringe barrel clamp mechanism (typical)
- Needle clamp assembly (typical)
- Mounting hardware for manipulator attachment (typical)
- User manual and setup instructions (typical)
Warranty
ConductScience provides a one-year manufacturer warranty covering defects in materials and workmanship, with technical support for setup and operational guidance.
Compliance
References
Background reading relevant to this product:
What syringe volumes are compatible with the 3-12 mm barrel clamp range?
The barrel clamp accommodates standard microinjection syringes from 1 μL to 100 μL volumes, covering Hamilton, SGE, and other precision syringes commonly used in stereotaxic procedures.
Can the needle clamp handle bent-tip cannulas for specific brain regions?
The 0.3-1.5 mm needle clamp can secure straight cannulas and needles. For bent-tip cannulas, verify that the clamp position does not interfere with the bend angle or injection trajectory.
How do I prevent needle clogging during viscous solution injections?
Use the largest compatible needle gauge (within the 0.3-1.5 mm range) for viscous solutions, inject slowly to reduce pressure buildup, and ensure the needle clamp provides adequate support without deforming the needle.
Is the holder compatible with automated injection pumps?
Yes, the holder provides stable syringe positioning for use with syringe pumps, though the pump's syringe compatibility must also fall within the 3-12 mm diameter range.
What maintenance is required for the clamping mechanisms?
Clean clamp surfaces with ethanol between uses, check for proper alignment monthly, and ensure clamp screws maintain appropriate tension without over-tightening.
Can I use this holder for bilateral simultaneous injections?
This single holder design is for unilateral injections. Bilateral procedures require two holders mounted on separate manipulator arms or a dual-arm stereotaxic system.
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