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Cytology
Laboratory Techniques

The Cytogenetics of Fungi

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Introduction Fungi is a group of eukaryotic organisms that include a myriad of single and multicellular organisms that are parasitic or saprophytic in nature. Over 1.5 million species of fungus have been discovered and they are found in a range of habitats. Some characteristic feature of fungus include: Ubiquitous
Cytology
Laboratory Techniques

Clinical Cytogenetics – Pt.2: A Study of Chromosomal Aberrations

Introduction Since the discovery of chromosomes, the cytogenetic field has evolved rapidly. The techniques have unfolded several hidden mysteries of chromosomes. And later, it gave rise to two branches: molecular and clinical cytogenetics. The studies in clinical cytogenetics suggested that the structural and numerical aberrations of chromosomes (autosomal and sex) are the cause of several abnormalities in human beings. For
Cytology
Laboratory Techniques

Clinical Cytogenetics – Pt.1: A study of chromosomal aberrations

Introduction As we know, cytogenetics is the study of chromosomal structure and behavior by using different staining techniques. In the year 1962, Lejeune proved Waardenburg’s hypothesis (the cause of Down syndrome could be a chromosomal aberration) by reporting the first case of syndrome due to chromosomal aberrations. It was a major breakthrough in cytogenetics research.[2] With the discovery of the
Nucleic Acid Quantification Protocols
Laboratory Techniques

Cytogenetics: An advanced technique to color Chromosomes

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Introduction Cytogenetics is the study of the structural and functional properties of the chromosome. It includes chromosomal structure, function, behavior - during mitosis and meiosis, and influence on the phenotype of an organism. It is used as a tool to understand genetic phenomena due to chromosomal aberrations. It combines
Nucleic Acid Quantification Protocols
Laboratory Techniques

Molecular Cytogenetics: in situ hybridization-based technology

Introduction Cytogenetics was introduced in 1900 as a tool to determine the correct number of chromosomes of an organism. Since the 1970s, it has been used to detect clinical syndromes; it helped to understand the chromosomal aberrations and phenotypes associated with it. Karyotyping was the first cytogenetics tool used to study the characteristics of chromosomes. But, the resolution of this