A tissue chopper is a cutting/slicing instrument used to cut fresh living tissue in cube slices and arterial rings without the need for freezing g or embedding.

The tissue chopper is an electrically powered appliance, and therefore the blade or cutting speed and slice thickness can be determined prior to operating the chopper. Adjustments to the blade speed, which is around 0-200 strokes per minute, are made by rotating a speed knob. The slice thickness can be calibrated on a micrometer head (1 micron – 25 micron).