Description
Product details
High Throughput: The system can stain up to 90 slides at once, significantly increasing laboratory efficiency.
Programmable Protocols: Offers 6 programmable sets, providing versatile choices for different staining procedures. It also allows for the simultaneous operation of 2 different programs.
Advanced Robotic Arm: The mechanical arm is designed to reduce dye carryover by up to 9 times, ensuring clean and accurate results.
Intuitive Touchscreen: A user-friendly color touchscreen simplifies data handling and operation.
Safety and Environment: Features an exhaust filtration system for purification, which helps to protect laboratory personnel from toxic fumes.
Flexible Operation: The system can easily switch between automatic and manual modes to accommodate specific needs.
Efficient Design: Single-cylinder covers minimize reagent evaporation, and wash and heating tanks ensure thorough reactions for better specimen quality.





Specifications
Model | RS-4 Fully Automated Slide Stainer |
Slide Capacity | Up to 90 slides (when two programs run simultaneously) |
Reagent Stations | Number of stations and their specific arrangement may vary; please refer to the product manual for exact details |
Programmable Sets | 6 programmable protocols |
Operation Mode | Automatic and Manual |
Control | Color Touchscreen |
Description
The Fully Automated Slide Stainers is a cutting-edge slide stainer designed for high-volume pathology and research labs. This fully automated system significantly enhances workflow by processing large quantities of samples efficiently, which saves time and resources. Beyond its high capacity, it guarantees uniform and consistent staining quality, eliminating the variations and errors often associated with manual methods.
With the RS-4, laboratories can handle demanding workloads with the confidence that every slide is processed with maximum precision, improving the reliability of diagnoses and research results. Its robust design and advanced features make it an indispensable solution for any facility looking to modernize and optimize its tissue staining processes.

Introduction
TheĀ RS-4 Fully Automated Slide Stainer represents a significant leap forward in histopathology technology, setting a new standard for efficiency and consistency in the lab. Designed to meet the high demands of both clinical and research environments, this system eliminates the manual effort and variability inherent in traditional staining methods. By automating the entire process, from deparaffinization to coverslipping, the RS-4 ensures every slide is processed with remarkable precision. This not only dramatically increases laboratory throughput but also enhances the reliability and quality of stained slides, providing pathologists and researchers with the clear, consistent results they need for accurate diagnoses and groundbreaking discoveries.
Characteristics
Principle | The RS-4 automates the hematoxylin and eosin (H&E) staining process; as well as special stains; by moving slide racks through a series of reagent stations. |
Compatibility | Designed for use with standard glass slides and various histological reagents. |
Stirring frequency | Adjustable 0ā6 times/min |
Efficiency | The ability to run two programs simultaneously allows for high throughput; making it suitable for high-volume labs. |
Safety | The internal exhaust filtration system ensures user safety by filtering out harmful fumes. |
Reliability | The mechanical arm and other components are engineered for stable operation and reliable performance. |
User-Friendly | The intuitive touchscreen interface and flexible operation modes make it easy to use for lab staff. |
Components
Main Unit with Robotic Arm: The core of the machine that automates the staining process.
Reagent Stations/Cups: Vats for holding the different dyes and solvents required for staining.
Slide Racks: Carriers for holding the slides during the staining process.
Wash and Heating Tanks: Integrated systems to ensure thorough rinsing and optimal reaction temperatures.
Touchscreen Interface: The control panel for programming and monitoring the staining runs.
Filtration System: An internal system for fume extraction.
Strengths and Limitations
Strengths
Efficiency and High Throughput: Automated systems process a large number of slides simultaneously, drastically reducing processing time and freeing up lab personnel for other critical tasks.
Consistency and Reproducibility: They eliminate the variability inherent in manual staining. Each sample is processed under the same controlled conditions of time and temperature, ensuring uniform and high-quality results in every batch.
Personnel Safety: Automated stainers minimize staff exposure to toxic reagents and fumes, as the systems are enclosed and often include air filtration systems. This significantly improves safety in the lab environment.
Reagent Savings: Automated systems are designed to use the minimum amount of reagent necessary for each stain, which reduces waste and lowers long-term operational costs.
Integration and Traceability: They allow for integration with laboratory information systems (LIS), which facilitates sample traceability and data management, minimizing identification errors.
Limitations
High Initial Cost: The upfront investment to acquire an automated staining system is considerably high, which can be a barrier for labs with limited budgets or low sample volume.
Maintenance and Technical Support: These machines require regular maintenance and, in case of failure, may need specialized technical support. This can lead to additional costs and potential downtime.
Vendor Dependency: The quality of service, reagents, and protocols is often tied to the equipment vendor. If a lab wishes to use reagents from a different supplier, it may require special adaptations or not be compatible.
Less Flexibility for Specialized Stains: While ideal for routine stains like H&E, the predefined protocols may offer less flexibility for highly specific or customized stains that might require a more hands-on, manual approach.
References
Domenico, G. (2018). Automation in Histopathology. AACC Press. https://www.aacc.org/store/books/automation-in-histopathology
Al-Janabi, O. M. A., & Al-Samarai, Y. A. J. (2023). A review on a tissue processor and an automatic slide stainer in Histopathology. Iraqi Journal of Medical Sciences, 21(2), 241-255. https://www.medj.uobaghdad.edu.iq/index.php/IraqiJMS/article/view/1749
Hamilton, T., et al. (2014). An objective assessment of a high-definition hematoxylin and eosin staining in a transition to digital pathology. Journal of Pathology Informatics, 5(1), 12. https://www.jpathinformatics.org/article.asp?issn=2153-0775;year=2014;volume=5;issue=1;spage=12;epage=12;aulast=Hamilton
Asem, E. K. (2019). Automation in Anatomic Pathology. Arch Pathol Lab Med, 143(6), 675-680. https://pubmed.ncbi.nlm.nih.gov/30811227/