Techniques

Quinolinic acid rat HD model
Laboratory Techniques

Quinolinic acid rat HD model

Introduction Huntington’s disease (HD) is an inherited autosomal dominant neuropathological disease caused by a mutation in the huntingtin gene (htt). Preclinical animal models are necessary for

3-Nitropreopionic acid Huntington’s disease model
Laboratory Techniques

3-Nitropreopionic acid Huntington’s disease model

Introduction 3-Nitropropionic acid (3-NP) is a selective striatal neurotoxin used in rodents to mimic pathological features of Huntington’s disease. 3-Nitropropionic acid interrupts the mitochondrial electron transport

Weight Drop Injury Model
Laboratory Techniques

Weight Drop Injury Model

Introduction Traumatic brain injury (TBI) is one of the most common brain injuries caused by an external impact or pressure, such as rapid acceleration or deceleration,

6-OHDA rat models
Laboratory Techniques

6-OHDA rat models

Parkinson’s disease (PD) is the most common neurological disorder that is characterized by debilitating motor abnormalities, including muscle rigidity, resting tumor, stiffer voluntary movements, and postural

Animal Models of Traumatic Brain Injury
Laboratory Techniques

Animal Models of Traumatic Brain Injury

Introduction The use of animal models for studying traumatic brain injury (TBI) has several advantages, including low breeding costs, easy maintenance, and innovative techniques to create

Rodent Craniotomy Protocol
Laboratory Techniques

Rodent Craniotomy Protocol

Introduction A craniotomy is a surgical procedure used to temporarily open a part of the skull to expose the brain for experimental manipulations. Research developments over

Fluid Percussion Injury
Laboratory Techniques

Fluid Percussion Injury

Need impactors for your experiments? Click here Introduction The fluid percussion injury (FPI) model is a widely used study model for traumatic brain injury. FPI model

HuntingtonÔÇÖs-Disease-Rodent-Models
Laboratory Techniques

Huntington’s Disease Rodent Models

Introduction ]Huntington’s disease (HD) is an inherited genetic neurological disorder characterized by cognitive dysfunction, abnormal body movements, progressive cell death, and neurodegeneration of the striatum and

ParkinsonÔÇÖs-Disease-Rat-Models
Laboratory Techniques

Parkinson’s Disease Rat Models

Introduction Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the loss of 50% to 70% of the dopaminergic neurons in the substantia nigra pars

Laboratory Techniques

Coomassie Brilliant Blue Stain Protocol

Introduction Coomassie brilliant blue (CBB) stain is a widely used method for routine visualization of proteins separated on polyacrylamide gels. It is an organic dye that

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