Description
Specifications
Model | Parameters | Standard Embedding RF-RD-98 | Advanced Embedding RF-RD-98PRO |
---|---|---|---|
Embedding Center: | Capacity of wax box: | 6 L | 12 L Three temperature sensors in the wax tank, dispensing tube, and tabletop. |
Temperature of wax chamber, wax pip, thermal chamber | Room temperature ~ 75°C | Room temperature ~ 75°C | |
Temperature Control Precision: | +1% | ±1°C. | |
Paraffin Flow Control: | finger touch plate and optional foot pedal | Includes a foot pedal for wax dispensing. | |
Dimensions of Paraffin Chamber | 270Ć150Ć150mm(W x DxH) | ||
Dimensions of Embedding Center | 620Ć560Ć410mm(W x Dx H) | 710mm x 670mm x 500mm, | |
Programmable timer | -- | Programmable timer for setting on/off times. | |
Wax tank level detection | -- | for real-time monitoring of remaining wax. | |
Quick wax melting function | -- | The wax tank enables rapid melting within a short time. | |
Cold plate: | Temperature of Cooling Plate | 0°C to -30°C | 0°C to -30°C |
Temperature setting of Cryo Module: | The optimal working temperature is approximately -10°C | The optimal working temperature is approximately -10°C | |
Maximum Number of Embedding Cassettes on Cooling Plate: | 70pcs | 70pcs | |
Dimensions of Cryo Module: | 620Ć380x410mm (WxDxH) | 690mm x 480mm x 440mm | |
Net weight: | 25kg | 40kq |
Features
Standard Embedding RF-RD-98
Advanced Embedding RF-RD-98PRO
Intuitive Touchscreen Control: Features a clear and easy-to-operate touchscreen display for efficient management.
Multi-Point Independent Heating: Provides independent temperature control for key areas like the wax box, wax tube, and heating stage.
Efficient Temperature Management: Utilizes an intelligent control system for accurate, quick, and smooth temperature rise.
Flexible Wax Dispensing: Supports convenient wax dispensing via both button and foot pedal methods.
Standard Wax Box Capacity: Equipped with a 5.5L (5500mL) wax box for daily use.
Powerful Cooling Plate: Includes a cooling plate capable of reaching atemperatures as low as ā30āC and holding approximately 70 cassettes
Advanced Touchscreen & Control: Features an LED touchscreen control panel for intuitive operation, allowing users to see all temperatures without scrolling.
Large Wax Tank Capacity: Equipped with a substantial 12L wax tank volume for higher throughput.
Enhanced Wax Dispensing & Safety: Includes a wax dispensing protection system with three temperature sensors and a dedicated wax dripping function.
Smart Monitoring & Melting: Offers wax tank liquid level detection for real-time monitoring and a quick wax melting function for rapid preparation.
Dual-Circuit Cooling System: Ensures stable tabletop temperature with a fluctuation of only ±1āC on the rapid cooling plate, which can reach ā30āC.
Programmable Automation: Features a fully programmable ON/OFF control for automatic system start and stop at any time.
Introduction
CS Tissue Embedding Stations are essential for the precise and efficient encapsulation of tissue specimens into paraffin blocks, a critical step in histology and pathology labs. The RD-98 series offers reliable solutions designed to streamline your embedding workflow, ensuring consistent and high-quality tissue sections. These stations feature intelligent temperature control systems and intuitive touchscreen interfaces for ease of use. Equipped with multi-point independent heating and efficient wax dispensing, they provide robust performance for various laboratory needs. Whether your lab requires standard capabilities or advanced features like larger wax tank capacities, enhanced safety systems, and dual-circuit cooling for superior precision, this series delivers ideal solutions for clinical, research, and educational environments focused on meticulous sample processing.
Parts of a Tissue Embedding Station Center
A typical tissue embedding station is composed of several key components, each designed to facilitate the precise encapsulation of tissue specimens in paraffin. These parts work together to create an efficient and controlled environment for the embedding process:
Control Panel / Touchscreen Display: This is the central interface for operating the machine, allowing users to monitor temperatures, adjust settings, and manage various functions.
Paraffin Tank / Wax Chamber: This heated reservoir holds the bulk supply of paraffin wax, keeping it in a molten state at a controlled temperature.
Paraffin Dispenser / Wax Nozzle: The outlet from which molten paraffin is dispensed into embedding molds. It often includes flow adjustment controls.
Heated Work Area / Hot Plate: A flat, heated surface where embedding molds and tissue cassettes are kept warm, preventing premature solidification of wax during tissue orientation.
Pre-warming Compartments (Left & Right Thermal Chambers): These heated slots or wells are designed to pre-warm forceps, cassettes, and other tools, ensuring they don’t cool the wax too quickly during embedding.
Cooling Plate / Cryo Module: A refrigerated surface used to rapidly cool and solidify the paraffin blocks after tissue orientation, preparing them for sectioning.
Wax Dispensing Mechanisms: Often includes both a manual dispensing lever or button and a foot pedal, offering hands-free control for dispensing paraffin.
Waste Tray / Residual Wax Recovery Drawer: Positioned beneath the work area to collect excess or spilled paraffin, ensuring a cleaner workstation and easy disposal.
Integrated Lighting: Provides clear illumination of the work area for precise tissue orientation.
Principle
The fundamental principle of a tissue embedding station lies in its precise control over temperature zones to manage paraffin and tissue specimens.
Paraffin Management: The station features a paraffin chamber that keeps the wax at a precisely controlled molten temperature, ready for dispensing. This ensures the wax is always at optimal viscosity for embedding.
Specimen Orientation: Heated work areas, including a hot plate and pre-warming compartments, maintain the tissue and embedding molds at temperatures that prevent premature solidification of the wax, allowing technicians to accurately orient the tissue within the mold.
Rapid Solidification: Once the tissue is correctly oriented and covered with molten paraffin, the mold is transferred to a cooling plate. This plate rapidly solidifies the paraffin block, fixing the tissue in place and creating a stable block suitable for microtomy.
Independent Control: Multiple working areas, such as the paraffin chamber, dispenser, hot plate, and cooling module, are individually controlled to maintain their specific optimal temperatures without interference.
Protocol
Operating a tissue embedding station effectively involves a series of systematic steps to ensure precise and high-quality tissue block preparation:
Pre-Operation Setup: Ensure the embedding station is clean and all heated zones (paraffin chamber, hot plate, pre-warming compartments) are set to their required temperatures and fully heated. The cooling plate should be activated and at its optimal temperature.Ā Ā
Dispensing Paraffin: Place an embedding mold onto the heated work area or hot plate. Activate the wax dispenser, either via the manual lever/button or foot pedal, to fill the mold with a small amount of molten paraffin.Ā
Tissue Orientation: Carefully transfer the processed tissue specimen from its cassette into the molten paraffin in the mold. Use pre-warmed forceps to precisely orient the tissue within the wax, ensuring it lies flat and in the correct plane for sectioning.Ā
Cassette Placement: Place the tissue cassette on top of the mold, creating the base of the paraffin block. Add more molten paraffin to completely fill the mold and cover the cassette, ensuring no air bubbles are trapped.Ā
Rapid Cooling: Once the block is formed, transfer the mold quickly to the cooling plate. The rapid cooling solidifies the paraffin, securing the tissue within a stable block ready for microtomy.Ā
Block Removal & Storage: Once fully solidified, remove the paraffin block from the mold. The block is now ready for storage or immediate sectioning.
Cleanup: After embedding, regularly clean the work surfaces and waste trays to maintain hygiene and optimal performance.
Strengths and Limitations
Strengths
Precise Temperature Control: Both RD-98 models feature intelligent control systems that ensure accurate and stable temperature regulation across all heated and cooled zones, crucial for optimal paraffin handling.
Multiple Independent Heating Zones: Equipped with numerous individually controlled heated areas, including the wax chamber, wax tube, heating stage, and preheating compartments, allowing for versatile workflow.
Efficient Wax Dispensing: Offers flexible wax dispensing methods, including both manual levers/buttons and a foot pedal for hands-free operation.
Rapid Block Solidification: The powerful cooling plate ensures quick solidification of paraffin blocks, reducing waiting times and improving lab efficiency.
ĀUser-Friendly Interface: Features intuitive touchscreen displays that make operation straightforward and parameter adjustments simple.
Programmable Operation: Includes convenient timing functions to automatically start and stop heating or cooling cycles, optimizing energy use and preparation time.
Robust Construction: Designed with durable materials for longevity and ease of cleaning.
Limitations
Dedicated Space: These stations require a dedicated area within the laboratory due to their size and specific function.
- Regular Maintenance: Consistent cleaning of wax residue and general maintenance are necessary to ensure the longevity and optimal performance of the machine.
- Specialized Use: These units are designed specifically for tissue embedding and may not be adaptable for other general laboratory tasks.
Summary
Here’s the summary for your Tissue Embedding Station page, presented with bullet points:
The Tissue Embedding Station is an essential piece of equipment in histology and anatomical pathology laboratories. Its primary function is to encapsulate processed tissue specimens into paraffin blocks, which is crucial for precise sectioning and microscopic analysis.
These stations operate by maintaining precise temperature zones for paraffin handling, allowing for accurate tissue orientation within molds on heated surfaces, followed by rapid solidification on cooling plates.
The RD-98 series features intelligent control systems, multi-point independent heating, and intuitive touchscreen displays for efficient operation. They offer flexible wax dispensing methods, including button and foot pedal controls.
The series includes the RD-98 model, providing robust and reliable performance with a 5.5L wax tank, and the RD-98 PRO, which offers advanced capabilities such as a 12L wax tank, enhanced wax dispensing safety, liquid level detection, and a dual-circuit cooling system for superior precision.
Both models are designed to ensure consistent, high-quality tissue block preparation, making them ideal for clinical, research, and educational environments
References
Chejfec, V., & Smith, S. G. (2018). Embedding Automation: Progress and Problems. American Journal of Clinical Pathology, 149(suppl_1), S91. https://academic.oup.com/ajcp/article-abstract/149/suppl_1/S91/4801504
Pantanowitz, L., et al. (2019). Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association. Archives of Pathology & Laboratory Medicine, 143(3), 325-334. https://pmc.ncbi.nlm.nih.gov/articles/PMC6437786/
Pantazis, P., & Thuc, N. H. (2025). Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control. MDPI, 11(8), 584. https://www.mdpi.com/2310-2861/11/8/584
Smith, E. A. F. C., Smith, P. M. F., & Smith, Z. (2025). Using digital pathology to standardize and automate histological evaluations of environmental samples. Oxford Academic. https://academic.oup.com/etc/article/44/2/306/7942823
Smith, R. I. S., Smith, P. M. F., & Smith, Z. (2022). Embedding brain tissue for routine histopathologyāa processing step worthy of consideration in the digital pathology era. PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC8946198/
Wang, Y., Qu, Y., & Cai, S. (2022). Digital light processing (DLP) in tissue engineering: From promise to reality, and perspectives. PubMed, 36179679. https://pubmed.ncbi.nlm.nih.gov/36179679/
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