1 / 3
Electric Von Frey
SKU ME-EVF-00
$3,190.00
IncludesStandard care
Electronic von Frey system for quantitative measurement of mechanical nociception thresholds using a single filament with variable pressure application from 0.08 mN to 2940 mN.
Scientist guidance
Louise Corscadden, PhD
Director of Science · ConductScience
Ask Louise about Electric Von Frey fit, setup, configuration, or quote prep.
Already working with us? Sign in to connect this with My Scientist.
Key Specifications
Full details →- Model fit
- Mouse, Rat
- SKU family
- ME-EVF-00
- Shipping box
- 43.2 x 38.0 x 27.9 cm
- Ordering
- Online checkout and quote request available
- Category
- Classic Mazes
- Build notes
- Confirm accessories, station layout, and support needs before purchase
The Electric Von Frey (EvF) is a quantitative mechanical nociception testing instrument that measures withdrawal thresholds in response to punctate mechanical stimuli. This electronic adaptation of the classical von Frey monofilament method employs a single filament capable of delivering variable pressure levels from 0.08 mN to 2940 mN, eliminating the need for multiple individual filaments.
The system enables precise assessment of mechanical allodynia and hyperalgesia through controlled application of force to the plantar surface of the paw. Unlike manual von Frey testing, the electronic version provides consistent, reproducible force application while maintaining the non-restraint testing protocol that minimizes handling-induced stress artifacts in behavioral measurements.
How It Works
The Electric Von Frey operates on the principle of controlled mechanical stimulation applied perpendicularly to the plantar surface of the paw. The instrument utilizes a single calibrated filament connected to an electronic force measurement system that precisely controls and records the applied pressure. When the filament contacts the skin and pressure is gradually increased, the system continuously monitors the force until a withdrawal response is detected.
The testing protocol typically employs the up-down method, where stimulus intensity is adjusted based on the response to the previous stimulus. The electronic system eliminates the buckling characteristic of manual von Frey filaments, instead providing linear force application across the full range of 0.08 mN to 2940 mN. This approach enables more precise determination of withdrawal thresholds compared to the discrete force levels available with manual filament sets.
The non-restraint testing protocol allows subjects to move freely while positioned on a wire mesh platform, reducing stress-induced confounding variables. The perpendicular application of force through the mesh to the plantar surface ensures consistent stimulus delivery while the electronic monitoring system captures withdrawal responses with high temporal resolution.
Features & Benefits
Single filament with variable pressure control
Eliminates need for multiple individual filaments, reducing testing time and improving measurement consistency across force ranges
Force range 0.08 mN to 2940 mN
Covers full spectrum of mechanical sensitivity testing from light touch to noxious pressure stimuli
Electronic force monitoring
Provides precise, real-time force measurement with digital recording capabilities for accurate threshold determination
Non-restraint testing protocol
Minimizes handling stress and anxiety that could confound nociceptive responses, improving data validity
Up-down method compatibility
Supports standard psychophysical testing protocols for efficient threshold determination with minimal stimulus presentations
Plantar surface application
Targets anatomically consistent testing site for reproducible measurements and comparison across studies
Withdrawal threshold measurement
Quantifies mechanical nociception with objective, measurable endpoints for statistical analysis
Add-ons and modifications
| Add-on | Price | Details |
|---|---|---|
| Electric Von Frey | $3,190 | Touch screen: high responsive capacitive touch screen Measurement precision: within 0.01 g Battery time: long battery time up to 8 hours; short time period for |
| Grid Platform | $1,490 | Includes a grid floor to examine mechanical nociception using the Electric or Manual Von Frey filaments. Holds up to 3 enclosures |
| Enclosure | $190 | Up to 4 mice or 2 rats per enclosure |
Add any of these to your quote request.
Force Range
- 0.08 mN to 2940 mN
Test Method
- Up-down method
Application Surface
- Plantar surface of the skin
Filament Type
- Single filament with varying pressure levels
Measurement Type
- Withdrawal thresholds
Assessment Capabilities
- Punctuating mechanical allodynia and hyperalgesia
Behavioral Construct
- mechanical nociception
- tactile sensitivity
- withdrawal threshold
- mechanical allodynia
- mechanical hyperalgesia
Automation Level
- semi-automated
Brand
- MazeEngineers
Research Domain
- Behavioral Pharmacology
- Neurodegeneration
- Neuroscience
- Pain Research
- Toxicology
Species
- Mouse
- Rat
Compatible Tracking Software
- ConductVision
Shipping weight
- 21.0 lb
Shipping box
- L: 43.2 cm
- W: 38.0 cm
- H: 27.9 cm
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Force Range | 0.08 mN to 2940 mN continuous range | Manual filament sets typically provide 10-20 discrete force levels | Enables more precise threshold determination without gaps between available stimulus intensities. |
| Filament System | Single electronic filament with variable pressure control | Multiple individual filaments with fixed force values | Reduces testing time and eliminates need to handle multiple filaments during threshold determination. |
| Force Monitoring | Real-time electronic force measurement and recording | Manual observation of filament buckling behavior | Provides objective force measurements and eliminates operator-dependent variability in buckling detection. |
| Testing Protocol | Up-down method with non-restraint positioning | Varies by system, some require restraint | Minimizes handling stress while maintaining standardized psychophysical testing approach. |
| Data Collection | Digital recording with withdrawal threshold measurement capabilities | Manual recording of responses and threshold calculations | Reduces transcription errors and enables automated threshold analysis for improved data quality. |
The Electric Von Frey provides continuous electronic force control across a wide stimulus range with real-time monitoring capabilities. The single-filament design streamlines testing protocols while maintaining the non-restraint approach essential for valid nociception measurements.
Pain Research
Quantitative assessment of mechanical allodynia and hyperalgesia in neuropathic pain models, providing precise withdrawal threshold measurements for drug efficacy studies.
Neuroscience
Evaluation of sensory function following spinal nerve ligation or other peripheral nerve injury models to characterize tactile sensitivity changes.
Behavioral Pharmacology
Assessment of analgesic compound efficacy by measuring changes in mechanical nociception thresholds before and after drug administration.
Toxicology
Detection of peripheral neuropathy induced by chemotherapeutic agents or other neurotoxic compounds through mechanical sensitivity testing.
Neurodegeneration
Monitoring progression of sensory deficits in diabetic neuropathy models by tracking mechanical withdrawal thresholds over time.
Practical Tips
Calibration
Perform calibration verification using known weights before each experimental session to ensure measurement accuracy.
Why: Force measurement precision is critical for reliable threshold determination and reproducible results across testing sessions.
Maintenance
Inspect filament probe regularly for damage or contamination and clean with appropriate disinfectant between subjects.
Why: Filament integrity directly affects force transmission and measurement accuracy.
Best Practices
Allow adequate habituation time on the testing platform and maintain consistent environmental conditions during testing.
Why: Stress and environmental factors can significantly influence nociceptive responses and threshold measurements.
Best Practices
Target the same plantar surface location consistently and avoid areas with obvious injury or callusing.
Why: Anatomical consistency is essential for reproducible measurements and valid comparisons between test sessions.
Data Quality
Record multiple threshold measurements per session and use appropriate statistical methods to determine representative values.
Why: Multiple measurements improve reliability and account for normal variability in nociceptive responses.
Troubleshooting
If withdrawal responses appear inconsistent, verify filament alignment and check for platform movement or vibration.
Why: Mechanical factors affecting stimulus delivery can introduce measurement artifacts and reduce data quality.
Safety
Set appropriate upper force limits to prevent tissue damage while ensuring adequate stimulus range for threshold detection.
Why: Subject welfare must be balanced with experimental requirements for meaningful nociceptive testing.
Setup Guide
Unpack and Inspect
Remove all components from packaging and verify the filament probe is undamaged and properly attached to the force measurement unit.
Position Testing Platform
Place the wire mesh testing platform at appropriate height and ensure stable positioning for subject placement.
Calibrate Force Settings
Perform system calibration according to manufacturer specifications to ensure accurate force measurements across the 0.08-2940 mN range.
Configure Data Recording
Set up data recording parameters including sampling rate, threshold detection criteria, and file output format.
Acclimate Test Subjects
Allow subjects to habituate to the testing environment and wire mesh platform for 10-15 minutes before beginning measurements.
Position Filament
Position the electronic filament probe beneath the wire mesh, ensuring perpendicular alignment with the plantar surface target area.
Initiate Testing Protocol
Begin testing sequence using the up-down method, starting with an appropriate initial force level based on experimental requirements.
What’s in the Box
- Electric Von Frey main unit (typical)
- Calibrated filament probe (typical)
- Wire mesh testing platform (typical)
- Power adapter (typical)
- USB data cable (typical)
- User manual and protocol guide (typical)
- Calibration certificate (typical)
Warranty
ConductScience provides a standard one-year manufacturer warranty covering defects in materials and workmanship, along with technical support for setup and protocol optimization.
Compliance
IASP Guidelines for Pain ResearchSupports standardized mechanical nociception testing protocols commonly used in pain research studies following International Association for the Study of Pain recommendations.
NIH Guidelines for Laboratory Animal CareEnables non-invasive sensory testing that aligns with principles of refinement in animal research by reducing handling stress and restraint requirements.
Q
How does the electronic system compare to manual von Frey filaments in terms of measurement precision?
A
The electronic system provides continuous force monitoring and eliminates the buckling behavior of manual filaments, enabling more precise threshold determination and reducing measurement variability between operators.
Q
What is the recommended testing protocol for establishing baseline withdrawal thresholds?
A
Use the up-down method starting with a mid-range force level, typically 2-4 mN, and adjust stimulus intensity based on response patterns until a stable threshold is established through multiple measurements.
Q
Can the system be calibrated for different force ranges or sensitivity requirements?
A
Yes, the electronic system supports calibration across the full 0.08-2940 mN range; consult product datasheet for specific calibration procedures and verification protocols.
Q
How should subjects be positioned to ensure consistent stimulus delivery?
A
Place subjects on the wire mesh platform allowing free movement while ensuring the plantar surface is accessible for perpendicular filament application; habituation period of 10-15 minutes is recommended.
Q
What data outputs are available for statistical analysis?
A
The system typically provides digital recording of force values, response times, and threshold measurements; consult product datasheet for specific data formats and export options.
Q
How frequently should the system be calibrated for research applications?
A
Regular calibration verification is recommended before each experimental series; specific calibration intervals depend on usage frequency and measurement precision requirements.
Q
Is the system suitable for longitudinal studies tracking threshold changes over time?
A
Yes, the electronic measurement consistency makes it well-suited for longitudinal assessments of mechanical sensitivity changes in chronic pain models or treatment studies.
Have a question about this product?
Track rodents with ConductVision
ConductVision is our video-tracking software. Record your sessions on video, and it scores standard rodent tests, such as those listed below.
Examples of tests it scores
To check whether ConductVision scores your protocol in this apparatus, ask in your quote request.
Ask a question
Have a question? Just ask.
Send it over and we'll email you a personalized answer — no call, no scheduling.
Personalized email reply
Usually within one business day
Helpful answers published here
Prefer to talk it through?
Accessories
Enhance your setup with compatible accessories
Total: $0.00
Creator Insights
Sandra R. ChaplanAuthored the quantitative von Frey monofilament method (1994, Yaksh lab)University of California, San Diego
About the Creator
Sandra R. Chaplan, Tally L. Yaksh and colleagues at the University of California, San Diego formalized the modern quantitative von Frey assay in a 1994 Journal of Neuroscience Methods paper, applying Dixon’s up-down method to a series of calibrated monofilaments to estimate a 50% paw-withdrawal threshold with high reproducibility, validated in a rat model of neuropathic pain. The technique builds on the calibrated “von Frey hairs” developed by the German physiologist Maximilian von Frey (1852–1932) at the University of Würzburg in the 1890s for mapping touch and pain thresholds. Electronic von Frey systems implement the same threshold logic with a force transducer. The Chaplan et al. (1994) method is now among the most cited papers in preclinical pain research.
To view Sandra R. Chaplan’s publications, visit PubMed.
Are you Sandra R. Chaplan? to review your photo and bio, and find out how to submit Creator Insights.
ConductScience celebrates method creators: researchers who, through rigorous and often ingenious experiments, develop the tools that reveal how the brain and body work. These are real scientific discoveries that become everyday instruments for the labs that follow.
Foundational paper
- Chaplan, S. R., Bach, F. W., Pogrel, J. W., Chung, J. M., & Yaksh, T. L. (1994). Quantitative assessment of tactile allodynia in the rat paw. Journal of Neuroscience Methods, 53(1), 55–63. doi:10.1016/0165-0270(94)90144-9
Use this apparatus with
The complete Electronic Von Frey workflow
Track behavior
No exact ConductVision von Frey page is currently published. Withdrawal events and force at withdrawal are normally captured by the instrument transducer rather than overhead tracking; keep this as a roadmap gap.
Supporting page not yet builtRun protocol
Enclosure habituation, probe-tip and ramp-rate settings, paw-targeting rules, trial spacing, and withdrawal-threshold scoring for the electronic von Frey assay.
ConductMaze Von Frey Protocol ->Analyze output
Summarize withdrawal threshold, withdrawal latency, response frequency, and paw-preference bias with quality-control flags.
Von Frey Up-Down Threshold Calculator ->Configuration considerations
Common Electronic Von Frey setup decisions
Use these notes to scope species, cohort, tracking, and automation needs. Only verified product or support routes are linked from this section.
This productElectronic
Electronic Von Frey
Handheld force transducer with a programmable ramp rate and digital threshold capture
Standard configuration for mechanical sensitivity and nociceptive threshold, recording the force at paw withdrawal as the probe ramps against the plantar surface.
Quote
Request QuoteBuyableMouse or rat
Species-Scaled Probe Set
Probe tips and force ranges scaled for mouse or rat plantar surface
Tip diameter and force range change how the stimulus loads the paw, so the probe set should match the species and the threshold range under study.
Quote
View options ->SpecialtyElevated mesh
Mesh-Floor Enclosure Array
Multi-compartment elevated mesh platform for plantar access during batch sessions
Best when throughput is the constraint, giving plantar access to several habituated animals at once while keeping each compartment visually separated.
Quote
Request automation help§ 1
Introduction
The Electronic Von Frey measures mechanical sensitivity by recording the force at which a rodent withdraws its paw from a ramping probe applied to the plantar surface. Chaplan and colleagues formalized quantitative threshold testing for tactile sensitivity, and the electronic transducer replaces a fixed filament series with a continuous force reading. 1
The primary readout is the withdrawal threshold, the force at the moment of withdrawal, complemented by withdrawal latency and response frequency to characterize the nociceptive threshold and any sensitization. Because the probe applies a graded force, the measure is continuous rather than stepped across discrete filaments. 1
Probe-tip geometry and ramp rate, enclosure habituation, locomotion and weight-bearing, observer cueing, and ambient temperature all change the recorded threshold independent of true sensitivity. A defensible protocol fixes the tip and ramp rate, habituates animals fully, applies a humane endpoint, and ideally uses a blinded observer. 1
§ 2
Methods
2.1 Procedure
Plantar mechanical stimulation with ramped force, fixed humane endpoint, and withdrawal-threshold scoring.
Pre-test setup
- 1.Enclosure habituation: Habituate animals to the elevated mesh enclosure across sessions until exploratory movement settles, so withdrawal reflects sensitivity rather than novelty or restlessness.
- 2.Probe and ramp setup: Fix the probe-tip diameter and the force ramp rate before testing, because both change how the stimulus loads the paw and shift the recorded threshold.
- 3.Define paw-targeting rule: Pre-define which plantar region is targeted and how left and right paws are sampled and counterbalanced, so paw-preference bias does not confound the threshold.
- 4.Set the humane endpoint: Set a maximum force ceiling as a humane endpoint so that an animal that does not withdraw is recorded at the ceiling rather than over-stimulated.
Trial sequence
- 1.Confirm weight-bearing: Apply the probe only when the paw is flat and weight-bearing, since a lifted or grooming paw gives a false withdrawal.
- 2.Ramp the force: Ramp force at the fixed rate against the plantar surface and capture the force at the moment of withdrawal as the threshold.1
- 3.Record latency and frequency: Log withdrawal latency and, across repeated trials, the response frequency that indexes sensitization.3
- 4.Alternate paws and rest: Alternate sampled paws with adequate inter-trial rest to avoid local sensitization and to keep paw sampling balanced.
- 5.Apply the humane endpoint: Stop at the force ceiling for any trial without withdrawal, record it as the ceiling value, and clean the enclosure between subjects.4
Critical methodological constraints
- Probe tip & ramp rate. Tip diameter and the rate of force increase change the recorded threshold. Hold both constant across all groups in a comparison.1
- Enclosure habituation. An unhabituated animal moves and withdraws to novelty rather than to the stimulus. Habituate to a stable baseline before testing.2
- Weight-bearing. Force must be applied to a flat, weight-bearing paw. A lifted, groomed, or shifted paw produces a false withdrawal that biases the threshold.
- Observer cueing. Threshold reading is observer-triggered. A blinded observer and a fixed withdrawal definition reduce cueing and rater variance.3
2.2 Measurement & Analysis
Core electronic von Frey endpoints for mechanical sensitivity, sensitization, and quality control.
Withdrawal Threshold
Mechanical sensitivity
Force at the moment of paw withdrawal, the primary mechanical-sensitivity readout on the continuous transducer.1
Withdrawal Latency
Response timing
Time from the start of the force ramp to withdrawal, complementing the threshold with a timing measure.
Response Frequency
Sensitization
Proportion of repeated stimulations that evoke a withdrawal, used as a sensitization index alongside the threshold.3
Paw-Preference Bias
Quality control
Difference in withdrawal between left and right paws, flagged so a postural or local bias is not read as a sensitivity change.
Ramp Rate Compliance
Stimulus control
Confirmation that each trial used the fixed force ramp rate, since ramp drift changes the recorded threshold.4
+ Additional metrics: probe-tip diameter, ceiling-force endpoint hits, ambient temperature, paw sampled, body weight, and per-enclosure habituation notes.
2.3 withdrawal frequency (analysis)
A compact fraction of stimulation trials that produced a paw withdrawal.
2.4 sample-size planning
Estimate the N per group needed to detect a literature-anchored sensitivity effect at the endpoint you plan to report. Override the defaults with your own pilot numbers.
§ 3
Results
PubMed publication counts, sample apparatus output, and recent papers from a dated PubMed snapshot.
3.1 Publication trends
PubMed volume and co-occurring behavioral methods for mechanical-sensitivity studies.
3.2 Sample apparatus output
Representative output from an electronic von Frey session on an elevated mesh floor.
3.3 Recent findings (PubMed)
- Sep 2026PMID: 42508527
Olfactory bulbectomy induces early allodynia and region-dependent astrocytic and microglial remodeling in female rats.
Cutiño-Viñals LM, Galindo-Paredes G, Gutiérrez-Figueroa FS, et al.. Neuroscience. 2026 Sep 28.
Major depressive disorder (MDD) frequently coexists with chronic pain in women. Olfactory bulbectomy (OBX) is a validated animal model of depression. In male rodents, OBX induces allodynia and glial alterations in the hippocampus and amygdala, and prefrontal cortex (PFC), regions implicated in MDD and pain processing.
- Sep 2026PMID: 42764519
Aerobic Exercise Prevents the Loss of Endogenous Pain Modulation in Male and Female Rats with Traumatic Brain Injury.
Irvine KA, Ferguson AR, Clark JD. J Neurotrauma. 2026 Sep 20.
Traumatic brain injury (TBI) patients may suffer from several long-term complications after injury such as impaired motor skills, cognitive decline, and sensory abnormalities including chronic pain.
- Sep 2026PMID: 42753900
Acupotomy alleviates perineural fibrosis, adhesion, and inflammation in experimental sciatic and vagus nerve adhesion models.
Chae H, Valappil AK, Kang IH, et al.. Exp Neurol. 2026 Sep 17.
Perineural adhesions resulting from surgery, trauma, or chronic inflammation can impair nerve mobility, promote fibrosis, and contribute to neuropathic pain and autonomic dysfunction. Effective minimally invasive therapeutic strategies for established neural adhesions remain limited.
- 2026PMID: 42765051
Single-Nucleus Transcriptomic Mapping Reveals Correlative Microglial Changes Associated with rTMS in the Motor Cortex After Spinal Cord Injury.
Zhang K, Yang X, Hou R, et al.. J Inflamm Res. 2026.
Spinal cord injury (SCI)-associated neuropathic pain (NP) is a severely disabling complication with limited treatment options.
- Sep 2026PMID: 42747734
Sacral Nerve Modulation Alleviates Neuropathic Pelvic Pain Through Modulation of the Spinal Immune Microenvironment and Microglial Activation.
Zuo J, Wang Y, Yang L, et al.. J Neuroimmune Pharmacol. 2026 Sep 16.
To investigate the efficacy of sacral neuromodulation (SNM) in alleviating neuropathic pelvic pain (NPP) and its underlying neuroimmune mechanisms, focusing on microglial activation and the CX3CL1-CX3CR1 pathway. A rat model of NPP was established via pelvic nerve crush (PNC), followed by SNM intervention.
- Sep 2026PMID: 42447745
Development of 2,8-diazaspiro[4.5]decan-3-ones as novel sigma-1 receptor antagonists and evaluation of antihyperalgesic effects.
Fu K, Pan R, Hu S, et al.. Bioorg Chem. 2026 Sep 15.
Hyperalgesia is a common clinical condition that can be alleviated by blocking the sigma-1 receptor (σ1R). This study focuses on designing a series of 2,8-diazaspiro[4.5]decan-3-one scaffold compounds derived from 4-IBP, with the aim of developing novel σ1R-selective analgesic antagonists.
§ 4
Discussion
Limitations of the paradigm, methodological caveats, and current directions.
4.1 Common confounds
Variables that can shift Electronic Von Frey results apart from the effect under study.
Probe tip & ramp rate
Tip diameter and the rate of force increase change the recorded threshold. Hold both constant across all groups.
Enclosure habituation
An unhabituated animal withdraws to novelty rather than to the stimulus. Habituate to a stable baseline before testing.
Locomotion/weight-bearing
Force must reach a flat, weight-bearing paw. A lifted or shifted paw gives a false withdrawal that biases the threshold.
Observer cueing
Threshold reading is observer-triggered. Blinding and a fixed withdrawal definition reduce cueing and rater variance.
Ambient temperature
Plantar and ambient temperature shift mechanical responsiveness. Standardize and report room temperature across sessions.
Preview exported markdown
## Electronic Von Frey — methods controls Confounds controlled in this protocol: - **Probe tip & ramp rate.** Tip diameter and the rate of force increase change the recorded threshold. Hold both constant across all groups. - **Enclosure habituation.** An unhabituated animal withdraws to novelty rather than to the stimulus. Habituate to a stable baseline before testing. - **Locomotion/weight-bearing.** Force must reach a flat, weight-bearing paw. A lifted or shifted paw gives a false withdrawal that biases the threshold. - **Observer cueing.** Threshold reading is observer-triggered. Blinding and a fixed withdrawal definition reduce cueing and rater variance. - **Ambient temperature.** Plantar and ambient temperature shift mechanical responsiveness. Standardize and report room temperature across sessions.
4.2 Construct validity caveats
The electronic von Frey is a research methods model of mechanical nociceptive sensitivity in rodents; it is not a clinical measure and clinical interpretation is out of scope. It is strongest when probe tip, ramp rate, habituation, and a humane force ceiling are fixed before testing, with paw sampling counterbalanced and an observer blinded to group. 1
4.3 Special considerations
When should I use the up-down method instead?
The continuous transducer gives a direct force at withdrawal, while the up-down method estimates a 50% threshold from a filament series. Use the up-down method when filaments are the standard for the model, and keep the chosen method constant across all groups.
How much habituation is enough?
Habituate across sessions until exploratory movement settles and baseline thresholds are stable. Testing an unsettled animal confounds sensitivity with novelty-driven withdrawal.
Why set a humane force ceiling?
A maximum force endpoint protects animals that do not withdraw and gives a defined ceiling value rather than over-stimulating the paw. Record ceiling hits as a welfare and quality-control outcome.
4.4 Current directions
Quarterly editorial review of emerging Electronic Von Frey methodology. Q2 2026
Methods
Ramp-rate standardization
Calibrating the force ramp rate across instruments improves comparability of withdrawal thresholds between labs and apparatus models.
Emerging
Automated withdrawal detection
Transducer-triggered withdrawal capture reduces observer cueing and records threshold, latency, and response frequency consistently.
Methods
Humane-endpoint reporting
Reporting the force ceiling and ceiling-endpoint hits is increasingly expected as a welfare and quality-control measure.
Emerging
Multi-assay sensory batteries
Mechanical sensitivity is paired with thermal nociceptive assays to separate mechanical and thermal sensory channels in the same cohort.
§ 5
References
6 selected methods and validation references for Electronic Von Frey.
- Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods. 1994;53(1):55-63. doi:10.1016/0165-0270(94)90144-9
- Deuis JR, Dvorakova LS, Vetter I. Methods used to evaluate pain behaviors in rodents. Front Mol Neurosci. 2017;10:284. doi:10.3389/fnmol.2017.00284
- Bonin RP, Bories C, De Koninck Y. A simplified up-down method (SUDO) for measuring mechanical nociceptive thresholds. Mol Pain. 2014;10:26. doi:10.1186/1744-8069-10-26
- Martinov T, Mack M, Sykes A, Chatterjea D. Measuring changes in tactile sensitivity in the hind paw of mice using an electronic von Frey apparatus. J Vis Exp. 2013;(82):e51212. doi:10.3791/51212
- Mogil JS. Animal models of pain: progress and challenges. Nat Rev Neurosci. 2009;10(4):283-294. doi:10.1038/nrn2606
- Barrot M. Tests and models of nociception and pain in rodents. Neuroscience. 2012;211:39-50. doi:10.1016/j.neuroscience.2011.12.041
Electric Von Frey
$3,190.00
Added to quoteView Quote
