The elevated plus maze test is one of the most widely used tests for measuring anxiety-like behavior. The test is based on the natural aversion of mice for open and elevated areas, as well as on their natural spontaneous exploratory behavior in novel environments. This test has a strong validity profile for anxiolytic drug validation and screening. All open arms include 1cm high end plates to ensure the mice do not fall off the maze during exploration.
MazeEngineers offers generic backlighting display cases for use with smaller mazes such as the open field, novel object recognition, and Y/T mazes. The sizing can be customized upon request for larger mazes as well. Please inquire for more information.
The Anesthesia Induction Chamber is used to confining the rodent in a closed space during anesthesia procedures. The chamber comes with a top sliding lid for convenient entry and removal of subjects, and two separate inlet and outlet openings for the entry of fresh anesthetizing gas and collection of scavenging waste gas material. The transparent material helps in visualizing the physical state of the subject; thus preventing accidental overdosing.
ConductScience offers the Anesthesia Induction Chamber.
Open Field test is a popular protocol used to assess exploratory behavior and anxiety. Thigmotaxis in the open field is used to evaluate anxiolytic, anxiogenic and even non-pharmacological treatments. Ambulation is the most common behavior studied with this maze, but others such as latency or rearing can also be measured. In addition, objects can be added for a modification similar to the novel object recognition field.
Walls can be both opaque or clear. We recommend that clear walls are used for measurements of anxiety, while opaque walls are used if assessments include novel object recognition.